Integrated herd management system utilizing isolated populations of X-chromosome bearing and Y-chromosome bearing spermatozoa

• US 20020096123A1
• Filed: 06/12/2001
• Published: 07/25/2002
• Est. Priority Date: 12/31/1997
• Status: Abandoned Application

• Current Assignee: XY Incorporated (Inguran LLC)
• Original Assignee: Colorado State University Research Foundation (Colorado State University System)
• Inventors: Whittier, Jack C., Burns, Patrick D., Riggs, Barbi A., Seidel, George
• Application Number:
  US09/879,480
• Publication Number:
  US 20020096123A1
• Time in Patent Office: Days
• US Class Current: 119/174
• CPC Class Codes: A01K 67/027 New or modified breeds of vertebrates
• CPC Class Codes: A61B 17/43 for artificial insemination
• CPC Class Codes: A61K 35/52 Sperm; Prostate; Seminal fluid; Leydig cells of testes
• CPC Class Codes: C12N 15/873 Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
• CPC Class Codes: C12N 5/0612 sorting of gametes, e.g. according to sex or motility
• CPC Class Codes: G01N 15/149 specially adapted for sorting particles, e.g. by their size or optical properties

Abstract

Animal management systems that utilizes artificial insemination (27) samples of isolated X-chromosome bearing and Y-chromosome bearing populations of spermatozoa to inseminate female animals (17) an embodiment of which can provide an alternative to traditional harvesting or marketing (20) of non-replacement heifers.

Claims

1. A method of managing animals, comprising the steps of:

a. producing a female of a species of mammal;

b. inseminating said female of said species of mammal with an artificial insemination sample having a plurality of spermatozoa, wherein at least 90% of said plurality of spermatozoa have a sex determination characteristic corresponding to the same sex of offspring mammal;

c. fertilizing at least one egg within said female of said species of mammal; and

d. producing said offspring mammal.

2. The method of managing animals as described in claim 1, wherein said sex determination characteristic comprises an X-chromosome.

3. The method of managing animals as described in claim 1, wherein said sex determination characteristic comprises an Y-chromosome.

4. The method of managing animals as described in claim 1, wherein said female of said species of mammal is selected from the group consisting of bovids, ovids, equids, canids, felids, and porcine.

5. The method of managing animals as described in claim 1, wherein said female of said species of mammal comprises a bovine species of mammal.

6. The method of managing animals as described in claim 5, wherein said plurality of spermatozoa comprises a number of spermatozoa selected from the group consisting of no more than 10 million live non-frozen spermatozoa, no more than 5 million live non-frozen spermatozoa, no more than 3 million live non-frozen spermatozoa, no more than 1 million live non-frozen spermatozoa, no more than 500,000 live non-frozen spermatozoa, no more than 250,000 live non-frozen spermatozoa, and no more than 100,000 live non-frozen spermatozoa.

7. The method of managing animals as described in claim 5, wherein said plurality of spermatozoa comprises a number of spermatozoa selected from the group consisting of no more than 10 million frozen-thawed spermatozoa, no more than 6 million frozen-thawed spermatozoa, no more than 5 million frozen-thawed spermatozoa, no more than 3 million frozen-thawed spermatozoa, no more than 1 million frozen-thawed spermatozoa, no more than 500,000 frozen-thawed spermatozoa, no more than 250,000 frozen-thawed spermatozoa, and no more than 100,000 frozen-thawed spermatozoa.

8. The method of managing animals as described in claim 1, wherein said female of said species of mammal comprises an equine species of mammal.

9. The method of managing animals as described in claim 6, wherein said plurality of spermatozoa comprises a number of spermatozoa selected from the group consisting of no more than 25 million live non-frozen spermatozoa, no more than 15 million live non-frozen spermatozoa, no more than 10 million live non-frozen spermatozoa, and no more than 5 million live non-frozen spermatozoa.

10. The method of managing animals as described in claim 6, wherein said plurality of spermatozoa comprises a number of spermatozoa selected from the group consisting of no more than 25 million frozen-thawed spermatozoa, no more than 15 million frozen-thawed spermatozoa, no more than 10 million frozen-thawed spermatozoa, and no more than 5 million frozen-thawed spermatozoa.

11. The method of managing animals as described in claim 1, wherein said plurality of spermatozoa comprises a number of spermatozoa from about 10% to about 50% relative to a typical number of spermatozoa in an artificial insemination sample.

12. The method of managing animals as described in claim 1, wherein said offspring mammal comprises a male, and wherein the percentage of male offspring mammals is selected from the group consisting of at least 70% male offspring mammals, at least 80% male offspring mammals, and at least 90% male offspring mammals.

13. The method of managing animals as described in claim 1, wherein said offspring mammal comprises a female, and wherein the percentage of female offspring mammals is selected from the group consisting of at least 70% female offspring mammals, at least 80% female offspring mammals, and at least 90% female offspring mammals.

14. The method of managing animals as described in claim 1, further comprising the step of inducing early puberty in said female of said species of mammal.

15. The method of managing animals as described in claim 14, wherein said female of said species of mammal comprises a female of a bovine species of mammal, and wherein said step of inducing early puberty in said female of said bovine species of mammal comprises inducing puberty by nine months after birth.

16. The method of managing animals as described in claim 14, wherein said step of inducing early puberty in said female of said bovine species of mammal comprises inducing said early puberty between about 250 days after birth to about 270 days after birth.

17. The method of managing animals as described in claim 14, wherein said step of inducing early puberty in said female of said bovine species of mammal comprises feeding said female of said bovine species of mammal a sufficient ration of feed to produce an average weight gain of about 1.3 kilograms per day to about 1.4 kilograms per day.

18. The method of managing animals as described in claim 14, further comprising the step of early weaning of said female of said species of mammal.

19. The method of managing animals as described in claim 18, wherein said female of said species of mammal comprises said female of said bovine species of mammal, and wherein said step of early weaning comprises weaning said female of said bovine species of mammal at between about 95 days to about 125 days after birth.

20. The method of managing animals as described in claim 18, wherein said step of inseminating said female of said bovine species of mammal comprises insemination of said female of said bovine species of mammal between about 283 days after birth to about 316 days after birth.

21. The method of managing animals as described in claim 18, further comprising the step of synchronizing estrous.

22. The method of managing animals as described in claim 21, wherein said step of synchronizing estrous comprises:

a. dressing feed with MGA at 0.5 milligrams per female of said bovine species of mammal per day for 14 days; and

b. injecting PGF2 19 days after the last day of dressing said feed with said MGA.

23. The method of managing animals as described in claim 22, further comprising the step of harvesting said female of said species of mammal.

24. The method of managing animals as described in claim 23, wherein said step of harvesting said female of said species of mammal comprises harvesting said female of said bovine species of mammal prior to 24 months.

25. The method of managing animals as described in claim 23, wherein said step of harvesting said female of said species of mammal comprises harvesting said female of said bovine species of mammal prior to 30 months.

26. The method of managing animals as described in claim 23, further comprising the step of replacing said female of said species of mammal with said offspring mammal.

27. The method of managing animals as described in claim 3, further comprising the step of harvesting said male offspring mammal.