Radiation treatment system and method of using same

• US 20020099363A1
• Filed: 01/23/2001
• Published: 07/25/2002
• Est. Priority Date: 01/23/2001
• Status: Abandoned Application

• Current Assignee: 21X Capital Ltd.
• Original Assignee: 21X Capital Ltd.
• Inventors: Milner, Mark S., Woodward, Benjamin W., Herekar, Satish V.
• Application Number:
  US09/770,094
• Publication Number:
  US 20020099363A1
• Time in Patent Office: Days
• US Class Current: 606/5
• CPC Class Codes: A61B 2090/064 for measuring force, pressure or mechanical tension
• CPC Class Codes: A61F 2009/00846 Eyetracking
• CPC Class Codes: A61F 2009/00853 Laser thermal keratoplasty or radial keratotomy
• CPC Class Codes: A61F 2009/00865 Sclera
• CPC Class Codes: A61F 2009/00872 Cornea
• CPC Class Codes: A61F 2009/00895 Presbyopia
• CPC Class Codes: A61F 9/0079 using non-laser electromagnetic radiation, e.g. non-coherent light or microwaves
• CPC Class Codes: A61F 9/008 using laser

Abstract

The present invention provides a system and associated method for advantageously treating bodily tissue containing collagen, such as ophthalmic tissue. The treatment includes providing a pattern of heating to which the tissue is to be exposed and the exposure of that tissue to shrink collagen therein. In ophthalmic applications, the pattern includes at least one region that corresponds to an ocular region of from about 4 mm to about 20 mm radially from the optical axis. The shrinkage of collagen within this ocular region improves accommodation for near vision. The present invention thus provides an effective treatment for the ocular condition of presbyopia.

Claims

1. A method of treating ocular tissue of an eye defining a central optical axis therethrough, comprising:

providing a pattern of heating according to which the ocular tissue is to be exposed, the pattern including at least one region of heating that corresponds to an ocular region within a radial distance of from about 4 mm to about 11 mm from the optical axis, and the heating sufficient to shrink collagen tissue within the ocular tissue; and

exposing the ocular tissue to the heating according to the corneal pattern to shrink collagen tissue within the ocular region thereby improving accommodation for near vision.

2. The method of claim 1, wherein the ocular tissue is corneal tissue and the pattern includes at least one region of heating that corresponds to a corneal region within a radial distance of from about 4 mm to about 6 mm from the optical axis.

3. The method of claim 1, wherein the ocular tissue is scleral tissue and the pattern includes at least one region of heating that corresponds to a scleral region within a radial distance of from about 6 mm to about 11 mm from the optical axis.

4. The method of claim 1, wherein the exposing of ocular tissue includes exposing the ocular tissue in a vicinity of a region in which ciliary muscle attaches to the ocular tissue.

5. The method of claim 1, wherein the exposing of ocular tissue causes the sclera to move in a direction away from an ocular lens of the eye.

6. The method of claim 1, wherein the exposing of ocular tissue creates a force in a direction outward from a limbus of the eye.

7. The method of claim 1, wherein the exposing of ocular tissue raises a temperature of collagen tissue within the exposed region to from about 55°

C. to about 100°

C.

8. The method of claim 1, wherein the exposing of ocular tissue raises a temperature of collagen tissue within the exposed region to from about 55°

C. to about 70°

C.

9. The method of claim 1, wherein the exposing of ocular tissue includes exposing the ocular tissue to heating from a source selected from a group consisting of a source of incoherent radiation, a source of radiofrequency radiation, a source of microwave radiation, a source of ultrasonic radiation, a tissue-contact source of thermal radiation, an electrical source of thermal radiation, a source of infrared radiation, a laser, and any combination thereof.

10. The method of claim 9, wherein the source is selected from a group consisting of a pulsed source and a continuous source.

11. The method of claim 1, wherein the exposing of ocular tissue improves a condition of presbyopia.

12. The method of claim 1, wherein a parameter of the exposing of ocular tissue is selected from a group consisting of a singular treatment region or a number of treatment regions, a size of a treatment region, a shape of a treatment region, a wavelength of radiation, an intensity of radiation, an intensity of heating, a singular pulse of radiation or a number of pulses of radiation from a pulsed source, a selection of a continuous source of heating, a period of exposure, and any combination thereof.

13. The method of claim 1, wherein the pattern is a pattern of radiation spots.

14. The method of claim 13, wherein the radiation spots have an effective diameter of about 0.4 mm to about 1.0 mm at a surface of the ocular tissue.

15. The method of claim 13, wherein a number of radiation spots is selected from a group consisting of eight or multiples of eight.

16. The method of claim 2, wherein the corneal pattern is a pattern of spots and a number of radiation spots is from about 8 to about 32.

17. The method of claim 3, wherein the scleral pattern is a pattern of spots and a number of radiation spots is from about 8 to about 64.

18. The method of claim 1, wherein an intraocular pressure of the eye is reduced.

19. The method of claim 1, wherein radiation of ocular tissue in a vicinity of trabecular meshwork of the eye is substantially avoided.

20. The method of claim 1, wherein the pattern is a substantially annular pattern.

21. The method of claim 20, wherein a source of the annular pattern is selected from a group consisting of a continuous source of the at least one region of heating and a pulsed source of the at least one region of heating.

22. The method of claim 20, wherein the substantially annular pattern is comprised of at least one region of radiation forming a substantially continuous annulus.

23. The method of claim 20, wherein the substantially annular pattern is comprised of overlapping regions of radiation.

24. The method of claim 1, wherein accommodation for near vision is improved by up to and including about 3 diopters.

25. The method of claim 1, wherein accommodation for near vision is improved by from one to five lines Snellen or Jaeger, or an amount corresponding thereto.