Percutaneous endarterectomy

• US 20020099396A1
• Filed: 01/22/2001
• Published: 07/25/2002
• Est. Priority Date: 01/22/2001
• Status: Active Grant

• Current Assignee: Boston Scientific Scimed, Inc. (Boston Scientific Corporation)
• Original Assignee: Scimed Life Systems Incorporated (Boston Scientific Corporation)
• Inventors: Lafontaine, Daniel M., Slaker, Bradley
• Granted Patent: US 6,719,775 B2
• Time in Patent Office: Days
• US Class Current: 606/159
• CPC Class Codes: A61B 17/22031 Gripping instruments, e.g. forceps, for removing or smashing calculi A61B17/221 takes precedence
• CPC Class Codes: A61B 17/22032 having inflatable gripping elements balloon catheters A61M25/10
• CPC Class Codes: A61B 17/320708 Curettes, e.g. hollow scraping instruments
• CPC Class Codes: A61B 2017/320044 Blunt dissectors
• CPC Class Codes: A61B 2017/320048 Balloon dissectors
• CPC Class Codes: A61B 2017/320741 for stripping the intima or the internal plaque from a blood vessel, e.g. for endarterectomy
• CPC Class Codes: A61B 2017/3435 using everted sleeves
• CPC Class Codes: A61M 2025/109 having balloons for removing solid matters, e.g. by grasping or scraping plaque, thrombus or other matters that obstruct the flow
• CPC Class Codes: A61M 25/0119 Eversible catheters
• CPC Class Codes: A61M 25/1006 Balloons formed between concentric tubes

Abstract

Methods and devices for separating plaque from vessel walls using everting membranes. Everting tubes disposed on catheters are used in one embodiment of the invention to separate plaque from blood vessel walls. One embodiment of the invention utilizes a single everting membrane including a fixed portion, a leading edge, and an advancing portion. The everting tube can have an interior which can be pressurized to propel the everting tube distal edge distally onward, so as to separate the plaque from the vessel inner wall. One device has double everting membranes fixedly attached to a tubular member and having facing advancing membrane portions which may be proximally fixed relative to one another, but are preferably both free to travel distally. The outermost tube can be laid down over the vessel inner wall and the innermost tube laid down over the plaque, with the advancing surfaces of each everting membrane facing each other. Fluid can be supplied under pressure to fill the interior of the everting tubes and thereby distally advance the tube leading edges. The present invention may be used in conjunction with distal emboli capturing filter or distal occlusion devices.

Claims

1. A method for separating plaque from a blood vessel, said blood vessel having an inner wall, said plaque having a body portion, said plaque being disposed along at least part of said vessel inner wall, the method comprising:

providing an everting membrane;

intravascularly inserting said everting membrane to near said plaque;

everting said membrane into a distally advancing portion, a distally leading edge, and a non-advancing portion, such that said distally advancing portion is distally advancing into said vessel, such that said leading edge is distally advancing into said vessel; and

advancing said advancing membrane portion and leading edge into said vessel along said vessel inner wall, such that said plaque is separated from said vessel inner wall.

2. A method for separating plaque from a blood vessel, the blood vessel having an inner wall, said plaque having a body portion, said plaque being disposed along at least part of said vessel inner wall, the method comprising:

providing an outer everting membrane tube having an outer tube distally leading edge;

providing an inner everting membrane tube having an outer tube distally leading edge, wherein said inner tube is disposed within said outer tube;

intravascularly inserting said inner and outer everting membrane tubes to near said plaque; and

distally advancing said inner and outer everting membrane tubes between said plaque body and said vessel inner wall by everting said inner and outer membrane tubes, such that said plaque is separated from said vessel inner wall.

3. A method for separating plaque from a blood vessel inner wall, said plaque having a body portion, said plaque being disposed along at least part of said vessel inner wall, the method comprising:

providing a membrane including an inner fold and an outer fold;

wherein said inner fold includes an inner fold inner portion, an inner fold outer portion and an inner fold distally leading edge disposed between said inner fold inner and outer portions;

wherein said outer fold includes an outer fold inner portion, an outer fold outer portion and an outer fold distally leading edge disposed between said outer fold inner and outer portions;

distally advancing said inner fold outer portion such that said inner fold leading edge is made to distally advance in between said plaque and said vessel wall; and

distally advancing said outer fold inner portion such that said outer fold leading edge is made to distally advance in between said plaque and said vessel wall.

4. A method for separating plaque from a blood vessel as in claim 3, wherein, during said distally advancing steps, said outer fold outer portion is maintained substantially immobile with respect to said vessel inner wall, wherein said inner fold inner portion is maintained substantially immobile with respect to said plaque.

5. A method for separating plaque from a blood vessel as in claim 3, wherein only one of said inner and outer folds are actively distally advanced, wherein the non-actively advanced fold is effectively distally moved by the actively advanced fold.

6. A method for separating plaque from a blood vessel as in claim 3, wherein said inner and outer folds are joined together at a location proximal of said outer fold inner portion and said outer fold outer portion.

7. A method for separating plaque from a blood vessel as in claim 3, wherein said inner and outer folds each have interior portions disposed within said inner and outer portions, wherein said inner and outer fold distally advancing step includes introducing fluid under pressure into at least one of said inner fold interior portion and outer fold interior portion.

8. A method for separating plaque from a blood vessel as in claim 3, wherein said inner and outer folds each have interior portions disposed within said inner and outer portions, wherein said inner and outer fold distally advancing steps include introducing fluid under pressure into said inner fold interior and said outer fold interior.

9. A method for separating plaque from a vessel inner wall comprising everting at least two membranes in between said plaque and said vessel inner wall.

10. A method for separating plaque from a vessel inner wall as in claim 9, further comprising intravascularly inserting said at least two membranes to a location near said plaque prior to said everting step.

11. A device for separating plaque from a vessel inner wall, the device comprising:

a tubular member having a distal region, and an inflation lumen,

a flexible membrane having a distal region secured to said tubular member distal region, and a proximal region slidably and sealably secured within said tubular member;

said flexible membrane having an interior disposed between said tube inner wall and said flexible membrane,

said flexible membrane interior being in fluid communication with said tube inflation lumen, such that supplying fluid under pressure to said tube inflation lumen causes said flexible membrane proximal region to travel distally toward said tube distal region.

12. An intravascular device for separating plaque from a vessel inner wall, the device comprising:

a tubular member having a distal region and an inflation lumen;

a flexible membrane including an inner fold and an outer fold, each fold having an interior and a distally leading edge;

said membrane inner fold having a proximal, distally advancing portion;

said membrane outer fold having a proximal, distally advancing portion, wherein said membrane inner and outer proximal distally advancing portions are coupled together; and

said inner fold and outer fold interiors being in fluid communication with said tube inflation lumen, such that supplying fluid under pressure to said inflation lumen causes said inner and outer fold distally leading edges to travel distally.