Carotid sinus nerve stimulation for epilepsy control

• US 20020103516A1
• Filed: 09/20/2001
• Published: 08/01/2002
• Est. Priority Date: 09/20/2000
• Status: Abandoned Application

• Current Assignee: UAB Research Foundation (University of Alabama System)
• Original Assignee: UAB Research Foundation (University of Alabama System)
• Inventors: Patwardhan, Ravish Vinay, Tubbs, Richard Shane
• Application Number:
  US09/957,566
• Publication Number:
  US 20020103516A1
• Time in Patent Office: Days
• US Class Current: 607/72
• CPC Class Codes: A61N 1/36064 Epilepsy
• CPC Class Codes: A61N 1/36157 Current A61N1/3616 takes precedence
• CPC Class Codes: A61N 1/36171 Frequency

Abstract

The present invention describes a method of treating, controlling or preventing epilepsy, comprising the steps of attaching at least one electrode to at least one of a patient'"'"'s carotid sinus nerves, and applying or modulating electric signals to or recording from at least one of the patient'"'"'s carotid sinus nerves through the at least one electrode, so as to treat, control, or prevent epilepsy.

Claims

1. A method of treating, controlling or preventing epilepsy and/or influencing neurological function, comprising the steps of attaching at least one electrode to afferents of at least one of a patient'"'"'s carotid sinus nerves, and applying modulating electric signals to at least one of the patient'"'"'s carotid sinus nerves through the at least one electrode, so as to treat, control, or prevent epilepsy.

2. The method of claim 1, including but not limited to the following modulating electric signals:

frequency of about 5 to about 300 cycles per second, at a constant current of between about 0.5 and about 20 milliamperes, and a pulse width of between about 0.1 and 1 millisecond.

3. The method of claim 1, wherein patients experiencing symptoms of an epileptic attack are treated by a process comprising the steps of:

detecting a physiological symptom associated with onset of a epileptic attack in a patient under treatment, and

selectively applying said modulating electric signals in response to detection of such symptom, as a programmed electrical stimulus to at least one of the patient'"'"'s carotid sinus nerves, for modulating electrical activity of preselected fibers of said nerve, in a manner to alleviate the epileptic attack.

4. The method of claim 1, wherein said electric signals are applied repeatedly over a period of time to thereby prevent or control such seizures.

5. The method of claim 1, wherein stimulation was conducted at the following parameters:

current 10 mA, frequency 40 Hz, pulsewidth 1 ms, time 10 seconds.

6. The method of claim 1, wherein the signal is applied utilizing a plurality of electrodes.

7. The method of claim 1 including the step of repeatedly applying said signal over a period of time.

8. The method of claim 1, whereby either external or internal instruments are used for carotid sinus nerve stimulation or recording.