Transluminal mitral annuloplasty

• US 20020103532A1
• Filed: 07/19/2001
• Published: 08/01/2002
• Est. Priority Date: 01/30/2001
• Status: Active Grant

• Current Assignee: Edwards Lifesciences AG (Edwards Lifesciences Corporation)
• Original Assignee: Edwards Lifesciences AG (Edwards Lifesciences Corporation)
• Inventors: Lesh, Michael D., Langberg, Jonathan J., Burg, Erik van der
• Granted Patent: US 6,810,882 B2
• Time in Patent Office: Days
• US Class Current: 623/2.36
• CPC Class Codes: A61F 2/2451 Inserts in the coronary sinus for correcting the valve shape
• CPC Class Codes: A61F 2/2466 Delivery devices therefor

Abstract

A mitral annuloplasty and left ventricle restriction device is designed to be transvenously advanced and deployed within the coronary sinus and in some embodiments other coronary veins. The device places tension on adjacent structures, reducing the diameter and/or limiting expansion of the mitral annulus and/or limiting diastolic expansion of the left ventricle. These effects may be beneficial for patients with dilated cardiomyopathy.

Claims

1. A method of performing transluminal mitral annuloplasty, comprising the steps of:

providing a catheter, having a prosthesis thereon;

inserting the catheter into the venous system;

transluminally advancing the prosthesis into the coronary sinus; and

rotating a component of the prosthesis to cause the prosthesis to exert a compressive force on the adjacent atrial musculature.

2. A method as in claim 1, further comprising the step of percutaneously accessing the venous system prior to the transluminally advancing step.

3. A method as in claim 2, wherein the accessing step is accomplished by accessing one of the internal jugular, subclavian and femoral veins.

4. A method as in claim 1, further comprising the steps of first measuring the coronary sinus and then selecting an appropriately sized prosthesis prior to the inserting step.

5. A method as in claim 1, further comprising the step of measuring hemodynamic function following the rotating step.

6. A method as in claim 5, further comprising the step of determining an ongoing drug therapy taking into account the post implantation hemodynamic function.

7. A method of providing a therapeutic compressive force against a tissue structure which is adjacent to a vessel wall, comprising the steps of positioning a device in the vessel;

rotating at least a part of a forming element within the device to cause the device to exert a force against the wall of the vessel thereby exerting a force against the adjacent tissue structure; and

deploying the device within the vessel.

8. A method as in claim 7, wherein the positioning step is accomplished percutaneously.

9. A method as in claim 7, wherein the tissue structure comprises the mitral valve annulus.

10. A method as in claim 7, wherein the tissue structure comprises the left ventricle.

11. A method as in claim 7, wherein the vessel comprises a vein.

13. A method as in claim 12, further comprising the step of percutaneously accessing the venous system prior to the positioning step.

14. A method as in claim 13, wherein the accessing step is accomplished by accessing one of the internal jugular, subclavian and femoral veins.

15. A method as in claim 12, wherein the locking step comprises engaging a first threaded surface with a second threaded surface.

16. A method as in claim 12, wherein the locking step comprises providing an interference fit.

17. A method as in claim 12, wherein the locking step comprises providing an adhesive bond.

18. A method as in claim 12, wherein the locking step comprises providing a knot.

19. A method as in claim 12, wherein the locking step comprises providing a compression fit.

20. A method as in claim 12, further comprising the steps of first measuring the coronary sinus and then selecting an appropriately sized prosthesis prior to the positioning step.

21. A method as in claim 12, further comprising the step of measuring hemodynamic function following the rotating step.

22. A method as in claim 21, further comprising the step of determining an ongoing drug therapy taking into account the post implantation hemodynamic function.

12. A method of performing annuloplasty of the mitral valve comprising positioning a prosthesis in the coronary sinus;

rotating a first portion of the device with respect to a second portion of the device to cause the device to bend into an arcuate configuration to provide a compressive force on the mitral valve annulus; and

securing the device in the arcuate configuration within the coronary sinus.