Method of filling a tube system with a rinsing liquid and a tube system for use with this method

• US 20020117189A1
• Filed: 04/16/2002
• Published: 08/29/2002
• Est. Priority Date: 05/29/1998
• Status: Abandoned Application

• Current Assignee: Bernd Mathieu, Claudia Ludt, Hans-Jurgen Neumann, Rudiger Witt, Thomas Pusinelli
• Original Assignee: Bernd Mathieu, Claudia Ludt, Hans-Jurgen Neumann, Rudiger Witt, Thomas Pusinelli
• Inventors: Neumann, Hans-Jurgen, Ludt, Claudia, Mathieu, Bernd, Pusinelli, Thomas, Witt, Rudiger
• Application Number:
  US10/123,920
• Publication Number:
  US 20020117189A1
• Time in Patent Office: Days
• US Class Current: 134/22.12
• CPC Class Codes: A61M 1/3643 Priming, rinsing before or after use
• CPC Class Codes: A61M 1/3644 Mode of operation
• CPC Class Codes: A61M 1/3646 Expelling the residual body fluid after use, e.g. back to the body
• CPC Class Codes: A61M 1/3647 with recirculation of the priming solution
• CPC Class Codes: A61M 2205/7527 liquophilic, hydrophilic
• CPC Class Codes: A61M 2205/7536 allowing gas passage, but preventing liquid passage, e.g. liquophobic, hydrophobic, water-repellent membranes

Abstract

A tube system comprising a blood inlet line with an arterial patient connection and a blood return line with a venous patient connection, where a rinsing liquid inlet line branches off from the blood inlet line downstream from the arterial patient connection, and a rinsing liquid return line branches off from the blood return line upstream from the venous patient connection is filled while maintaining sterility in that rinsing liquid is pumped from a rinsing liquid container through the rinsing liquid inlet line, the blood inlet line, the blood return line and the rinsing liquid return line, establishing a liquid connection between the rinsing liquid inlet line and return line. The venous patient connection is sealed liquid-tight with a venous safety cap, and the arterial patient connection is sealed liquid-tight with an arterial safety cap. The safety caps are removed from the patient connections for connecting the tube system to the patient.

Claims

1. A method of filling a tube system with a rinsing liquid while maintaining sterility of the tube system, the tube system including a blood inlet line with an arterial patient connection, a blood return line with a venous patient connection, a rinsing liquid inlet line branching off from the blood inlet line downstream from the arterial patient connection, and a rinsing liquid return line branching off from the blood return line upstream from the venous patient connection, the method comprising the steps of:

conveying rinsing liquid from a rinsing liquid container into the rinsing liquid inlet line, establishing a liquid connection between the rinsing liquid inlet and the rinsing liquid return line, forming a liquid-tight seal for the venous patient connection with a venous safety cap, and forming a liquid-tight seal for the arterial patient connection with an arterial safety cap, wherein the venous safety cap and the arterial safety cap are removable from the venous and arterial patient connections.

2. The method according to claim 1 wherein the establishing step includes conveying the rinsing liquid from the rinsing liquid return line through the rinsing liquid container into the rinsing liquid inlet line.

3. The method according to claim 1 wherein the establishing step includes conveying the rinsing liquid from the rinsing liquid return line into the rinsing liquid inlet line, bypassing the rinsing liquid container.

4. The method according to claim 1 wherein the conveying step includes pumping the rinsing liquid out of the rinsing liquid container using a blood pump connected to the blood inlet line.

5. The method according to claim 1 wherein the rinsing liquid return line branches off from the blood return line at a first branch, and air in a line section of the blood return line downstream from the first branch is released from the venous safety cap so that the venous safety cap is filled with the rinsing liquid.

6. The method according to claim 5 wherein the air being released from the venous safety cap is transferred from the venous safety cap to the arterial safety cap so as to establish an air-permeable but liquid-impermeable connection between the venous and arterial safety caps.

7. The method according to claim 1 wherein the conveying step includes conveying the rinsing liquid out of the rinsing liquid container and into the blood inlet line through the rinsing liquid inlet line under an influence of gravity, while air in a line section of the blood inlet line upstream from a branch in the rinsing liquid inlet line is released from the arterial safety cap so that the arterial safety cap is filled with the rinsing liquid, and sealing the blood inlet line airtight and pumping the rinsing liquid out of the rinsing liquid container by a blood pump connected to the blood inlet line.

8. The method according to claim 7 wherein the venous safety cap is filled with rinsing liquid by recirculating the rinsing liquid.

9. A tube system comprising:

a blood inlet line having an arterial patient connection;

an arterial safety cap for liquid-tight sealing of the arterial patient connection, the arterial safety cap being removable from the arterial patient connection for connecting the tube system,

a blood return line having a venous patient connection;

a venous safety cap for liquid-tight sealing of the venous patient connection, the venous safety cap being removable from the venous patient connection for connecting the tube system;

a rinsing liquid inlet line branching off from the blood inlet line downstream from the arterial patient connection and a rinsing liquid return line branching off from the blood return line upstream from the venous patient connection, the rinsing liquid inlet line and the rinsing liquid return line being connected to a rinsing liquid container for accommodating rinsing liquid;

a first cut-off device being connected to the rinsing liquid inlet line downstream from the rinsing liquid container;

a second cut-off device being connected to the rinsing liquid return line upstream from the rinsing liquid container;

a short-circuit line connecting the rinsing liquid inlet line and the rinsing liquid return line; and

at least one of a third cut-off device and a pressure control valve being connected to the short-circuit line.

10. The tube system according to claim 9 further comprising a first drip chamber arranged in the rinsing liquid inlet line upstream from the first cut-off device and a second drip chamber arranged in the rinsing liquid return line downstream from the second cut-off device.

11. The tube system according to claim 10 wherein a first end of the short-circuit line branches off from an inlet line section of the rinsing liquid inlet line between the first drip chamber and the first cut-off device, and a second end of the short-circuit line branches off from a return line section of the rinsing liquid return line upstream of the second cut-off device.

12. The tube system according to claim 10 wherein a first end of the short-circuit line branches off from an inlet line section of the rinsing liquid inlet line downstream from the first cut-off device, and a second end of the short-circuit line branches off from an inlet line section of the rinsing liquid return line upstream from the second cut-off device.

13. The tube system according to claim 9 wherein the venous safety cap has an air outlet orifice sealed with a hydrophobic membrane.

14. The tube system according to claim 9 wherein the arterial safety cap has an air outlet orifice sealed by a hydrophobic membrane, an inside of the hydrophobic membrane being covered with a hydrophilic membrane.

15. The tube system according to claim 9 wherein the venous and arterial safety caps are designed in one piece having an interior venous chamber and an interior arterial chamber.

16. The tube system according to claim 9 wherein the venous and arterial safety caps are designed in one piece having an interior venous chamber and an interior arterial chamber, the interior arterial chamber being connected to the interior venous chamber through a hydrophobic membrane.

17. The tube system according to claim 9 wherein at least one of the venous and arterial patient connections has a cannula for connection to a patient, the cannula being surrounded in a sterile manner.

19. The tube system according to claim 18 further comprising a drip chamber arranged in the rinsing liquid inlet line between the rinsing liquid container and the first cut-off device.

20. The tube system according to claim 18 wherein the venous safety cap has an air outlet orifice sealed with a hydrophobic membrane.

21. The tube system according to claim 18 wherein the arterial safety cap has an air outlet orifice sealed by a hydrophobic membrane, an inside of the hydrophobic membrane being covered with a hydrophilic membrane.

22. The tube system according to claim 18 wherein the venous and arterial safety caps are arranged in one piece having an interior venous and arterial chamber.

23. The tube system according to claim 18 wherein the venous and arterial safety caps are arranged in one piece having an interior venous and an arterial chamber, the interior arterial chamber being connected to the interior venous chamber through a hydrophobic membrane.

24. The tube system according to claim 18 wherein at least one of the venous and arterial patient connections has a cannula for connection to a patient, the cannula being provided in a sterile manner.

26. The safety cap unit according to claim 25 wherein the interior arterial chamber is connected to the environment by a second hydrophobic membrane.

18. A tube system comprising:

a blood inlet line having an arterial patient connection;

an arterial safety cap for liquid-tight sealing of the arterial patient connection, the arterial safety cap being removable for connecting the tube system;

a blood return line having a venous patient connection;

a venous safety cap for liquid-tight sealing of the venous patient connection, the venous safety cap being removable from the venous patient connection for connecting the tube system;

a rinsing liquid inlet line branching off from the blood inlet line downstream from the arterial patient connection and a rinsing liquid return line branching off from the blood return line upstream from the venous patient connection and having a free end, the rinsing liquid inlet line being connected to a rinsing liquid container for accommodating the rinsing liquid;

a first cut-off device being connected to the rinsing liquid inlet line downstream from the rinsing liquid container, the rinsing liquid inlet line between the rinsing liquid container and the first cut-off device defining a line section of the rinsing liquid inlet line, the free end of the rinsing liquid return line being connected to the line section; and

a second cut-off device connected to the rinsing liquid return line.

25. A safety cap unit for a tube system comprising:

an interior venous chamber for accommodating a venous patient connection; and

an interior arterial chamber for accommodating an arterial patient connection of the tube system under sterile conditions, the interior venous chamber being connected to an environment by a hydrophobic membrane.

27. A safety cap unit for a tube system comprising:

an interior venous chamber for accommodating a venous patient connection; and

an interior arterial chamber for accommodating an arterial patient connection of the tube system under sterile conditions, the interior venous chamber being connected to the interior arterial chamber by a hydrophobic membrane.