Diffusion barrier layer for implantable devices
First Claim
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1. A method of forming a coating supported by an implantable device, comprising the acts of:
- applying a first composition containing particles to an implantable device to form a coating containing the particles, wherein the coating containing the particles acts as a rate reducing membrane for the release of an active ingredient.
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Abstract
A diffusion barrier for an implantable device, such as a stent, carrying a therapeutic or bioactive substance is disclosed. The diffusion barrier reduces the rate at which the therapeutic or bioactive substance is released from the device. The diffusion barrier can be made from a polymeric material impregnated with particles.
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Citations
32 Claims
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1. A method of forming a coating supported by an implantable device, comprising the acts of:
applying a first composition containing particles to an implantable device to form a coating containing the particles, wherein the coating containing the particles acts as a rate reducing membrane for the release of an active ingredient. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29)
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13. A stent, comprising a first coating containing particles, wherein the first coating acts as a diffusion barrier for an active ingredient.
- 30. A coating for a prosthesis for reducing the rate at which an agent travels through the coating comprising inorganic particles disposed in the coating.
Specification