Methods and devices for high throughput fluid delivery
First Claim
Patent Images
1. A microfluidic device, comprising:
- a body structure comprising at least one microchannel network and a plurality of ports disposed in the body structure, at least one port being in fluid communication with at least one microchannel in the at least one microchannel network; and
, a manifold comprising at least one manifold channel network and at least one aperture disposed in the manifold, the at least one aperture being in fluid communication with at least one manifold channel in the manifold channel network, the manifold being mated with the body structure, whereby the at least one aperture or one or more manifold channels in the manifold channel network is in fluid communication with one or more of the plurality of ports.
2 Assignments
0 Petitions
Accused Products
Abstract
Methods and devices for delivering fluids into microfluidic device body structures are described. The methods and devices include the use of fluid manifolds which are integrated or interchangeable with device body structures. Methods of fabricating manifolds are also provided.
-
Citations
55 Claims
-
1. A microfluidic device, comprising:
-
a body structure comprising at least one microchannel network and a plurality of ports disposed in the body structure, at least one port being in fluid communication with at least one microchannel in the at least one microchannel network; and
,a manifold comprising at least one manifold channel network and at least one aperture disposed in the manifold, the at least one aperture being in fluid communication with at least one manifold channel in the manifold channel network, the manifold being mated with the body structure, whereby the at least one aperture or one or more manifold channels in the manifold channel network is in fluid communication with one or more of the plurality of ports. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51)
-
-
37. A method of distributing at least one fluid to one or more of a plurality of ports disposed in a body structure of a microfluidic device, the method comprising:
-
loading the at least one fluid into at least a first aperture in a manifold of the microfluidic device, which microfluidic device comprises the manifold and the body structure, wherein the manifold further comprises at least one manifold channel network disposed therein, wherein the first aperture is in fluid communication with one or more manifold channels in the at least one manifold channel network, wherein the first aperture or at least one manifold channel is in fluid communication with the one or more of the plurality of ports, and wherein at least one microchannel network is in fluid communication with the plurality of ports; and
,flowing the at least one fluid using at least one fluid direction component from the first aperture through the at least one manifold channel network such that the at least one fluid is distributed to the one or more of the plurality of ports disposed in the body structure of the microfluidic device.
-
- 52. A method of fabricating a manifold for a microfluidic device, the method comprising forming one or more layers using at least one fabrication process to comprise at least one aperture disposed in the one or more layers, which aperture is in fluid communication with one or more manifold channel networks disposed in at least one of the one or more layers, wherein the manifold is structurally configured to mate with a body structure of the microfluidic device.
Specification