Biosensors, reagents and diagnostic applications of directed evolution

• US 20020127623A1
• Filed: 07/31/2001
• Published: 09/12/2002
• Est. Priority Date: 07/31/2000
• Status: Abandoned Application

• Current Assignee: Codexis, Inc.
• Original Assignee: Maxygen Inc.
• Inventors: Krebber, Claus, Minshull, Jeremy, Davis, S. Christopher, Welch, Mark, Raillard, Sun Ai, Vogel, Kurt
• Application Number:
  US09/920,607
• Publication Number:
  US 20020127623A1
• Time in Patent Office: Days
• US Class Current: 435/7.92
• CPC Class Codes: C12N 15/1055 Protein x Protein interaction, e.g. two hybrid selection
• CPC Class Codes: C12N 9/1252 DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
• CPC Class Codes: C12P 19/34 Polynucleotides, e.g. nucleic acids, oligoribonucleotides
• CPC Class Codes: C12Q 1/6888 for detection or identification of organisms

Abstract

Methods for sensing test stimuli using arrays of biopolymers are provided. Libraries of biopolymers, such nucleic acid variants, and expression products encoded by nucleic acid variants are provided. Reusable library arrays, and methods for their use are provided.

Claims