Implantable sensor
First Claim
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1. A blood glucose detector for implantation within a blood vessel, comprising:
- at least two supports, each having a first side for contacting the wall of the vessel and a second side for facing radially inwardly toward the center of the vessel;
and a sensor located between at least two supports and having a sensing surface thereon;
wherein the sensing surface is spaced radially inwardly from the first side by a distance of at least about 0.2 mm, such that the velocity of blood in the vessel inhibits obstruction of the sensing surface.
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Abstract
A sensor is disclosed, for implantation within a blood vessel to monitor an analyte in blood. In one embodiment, the analyte is glucose. A signal indicative of glucose level is transmitted to an external receiver. The signal may also be used to drive an internal or externally worn insulin pump. Methods are also disclosed.
394 Citations
44 Claims
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1. A blood glucose detector for implantation within a blood vessel, comprising:
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at least two supports, each having a first side for contacting the wall of the vessel and a second side for facing radially inwardly toward the center of the vessel;
and a sensor located between at least two supports and having a sensing surface thereon;
wherein the sensing surface is spaced radially inwardly from the first side by a distance of at least about 0.2 mm, such that the velocity of blood in the vessel inhibits obstruction of the sensing surface. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30)
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19. An implantable sensor for sensing the presence of an analyte in a vessel, comprising:
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at least two substantially tubular support structures for anchoring the sensor in the vessel, each support structure having a side wall with a luminal side facing toward the center of the vessel and an abluminal side facing toward the wall of the vessel;
a sensor housing carried by the support structures, the housing having a streamlined exterior configuration to minimize blood flow turbulence and located between two support structures;
a power supply and electrical circuitry in the housing; and
a sensing surface exposed to the exterior of the housing;
wherein the sensing surface is positioned on the radially inwardly most portion of the luminal side of the housing.
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- 31. A method of reducing the cross sectional profile of an intraluminal electronic device, comprising the steps of packaging the device in at least two separate components, and securing the components to at least a first anchor and a second anchor for retaining the components axially spaced apart within the lumen.
- 33. A method of reducing the cross sectional profile of an intraluminal electronic device, comprising the steps of positioning the device at a site in a lumen, and activating a first anchor on a first side of the device and a second anchor on a second side of the device to retain the device in the lumen.
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39. An intraluminal electronic device, comprising a first housing having a first anchor on a proximal side of the housing and a second anchor on a distal side of the housing, wherein the first and second anchors are axially separated by at least the axial length of the housing.
Specification