Microstructured dual sided membrane for tissue growth and regeneration
First Claim
1. An article for use in healing of wounds and repair of tissue defects, the article comprising:
- (a) a flexible membrane having an upper and a lower surface, each surface defining a substrate formed of a biologically-acceptable biodegradable material adapted to be resorbed in use, each substrate having thereon means capable of orienting cell growth comprising a microgeometry formed in said substrates, a microgeometry of said upper surface proportioned to a cell morphology of soft tissue cells and a microgeometry of said lower surface proportioned to a cell morphology of bone tissue cells.
3 Assignments
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Accused Products
Abstract
An implantable substantially planar bioabsorbable article for the separation and regeneration of tissue at a tissue defect site includes first surface of the article, which may be circular or elliptical, that is provided with a soft tissue side intended for direction towards soft or subcutaneous tissue and having a microtextured surface optimized for promotion of ingrowth of soft tissue. An opposite side of the article comprises a different microgrooved surface, optionally including osteoconductive chemical properties, and physically oriented against or within the bone defect site toward and against the center of the defect into which any graft material placed. The membrane is flexible and of sufficient density to accommodate sutures or is circumfentially provided with perforations to hold sutures.
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Citations
10 Claims
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1. An article for use in healing of wounds and repair of tissue defects, the article comprising:
(a) a flexible membrane having an upper and a lower surface, each surface defining a substrate formed of a biologically-acceptable biodegradable material adapted to be resorbed in use, each substrate having thereon means capable of orienting cell growth comprising a microgeometry formed in said substrates, a microgeometry of said upper surface proportioned to a cell morphology of soft tissue cells and a microgeometry of said lower surface proportioned to a cell morphology of bone tissue cells. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
Specification