Database system and method

• US 20020133495A1
• Filed: 03/13/2001
• Published: 09/19/2002
• Est. Priority Date: 03/16/2000
• Status: Abandoned Application

• Current Assignee: Genaissance Pharmaceuticals Incorporated (Abbvie Incorporated)
• Original Assignee: Genaissance Pharmaceuticals Incorporated (Abbvie Incorporated)
• Inventors: Kean, James R., Rienhoff, Hugh Y. Jr., Jones, Hywel B.
• Application Number:
  US09/805,813
• Publication Number:
  US 20020133495A1
• Time in Patent Office: Days
• US Class Current: 707/100
• CPC Class Codes: G16B 20/00 ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
• CPC Class Codes: G16B 20/20 Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
• CPC Class Codes: G16B 50/00 ICT programming tools or database systems specially adapted for bioinformatics
• CPC Class Codes: G16H 70/00 ICT specially adapted for the handling or processing of medical references

Abstract

A secured database is populated with genotypic and phenotypic data using a server coupled with a world wide network of computers. The server provides a web site configured to create trust of the web site by users. Users are invited to submit phenotypic data, and users are invited to submit a biological sample. The secured database is populated with received phenotypic data, and received biological samples are analyzed to obtain genetic data. The secured database is populated with the genetic data obtained from biological samples. Users that previously submitted phenotypic data are prompted to submit new phenotypic data, and the secured database is populated with the received prompted new phenotypic data. The secured database is prompted with received unprompted new phenotypic data.

Claims

1. A method for populating a secured database with genotypic and phenotypic data using a server coupled with a world wide network of computers, the server providing a web site configured to create trust of the web site by users, the method comprising:

inviting users to submit phenotypic data;

inviting users to submit a biological sample;

populating the secured database with received phenotypic data;

analyzing received biological samples to obtain genetic data;

populating the secured database with the genetic data obtained from biological samples;

prompting users that previously submitted phenotypic data to submit new phenotypic data; and

populating the secured database with received prompted new phenotypic data.

2. The method of claim 1 further comprising populating the secured database with received unprompted new phenotypic data.

3. The method of claim 1 further comprising identifying a subset of the users that previously submitted phenotypic data from which to invite submitting a biological sample, wherein only the subset of users is invited to submit a biological sample.

4. The method of claim 1 further comprising identifying a subset of the users that previously submitted phenotypic data from which to request additional phenotypic data, wherein only the subset of users is prompted to submit new phenotypic data.

5. The method of claim 1 further comprising:

analyzing received biological samples to obtain phenotypic data; and

populating the secured database with the phenotypic data obtained from biological samples.

6. The method of claim 1 further comprising:

prompting users that previously submitted biological samples to submit a new biological sample;

analyzing received new biological samples to obtain phenotypic data; and

populating the secured database with the phenotypic data obtained from new biological samples.

7. The method of claim 6 further comprising identifying a subset of the users that previously submitted phenotypic data and previously submitted a biological sample from which to invite submitting a new biological sample, wherein only the subset of users is prompted to submit a biological sample.

8. A method for populating a secured database with genotypic and phenotypic data, the method comprising:

providing a server coupled with a world wide network of computers;

providing a web site configured to create trust of the web site by users;

identifying prospective volunteers from amongst the users of the web site;

inviting the prospective volunteers to submit phenotypic data and biological samples;

populating the secured database with the received phenotypic data;

analyzing received biological samples from volunteers to obtain genetic information;

populating the secured database with the genetic information;

prompting the volunteers to provide new phenotypic data; and

receiving the prompted new phenotypic data and populating the secured database with the prompted new phenotypic data.

9. The method of claim 8 wherein the new phenotypic data includes data that adds to data previously submitted.

10. The method of claim 8 wherein the new phenotypic data includes data that modifies data previously submitted.

11. The method of claim 8 further comprising receiving unprompted new phenotypic data via the world wide network of computers and populating the secured database with the unprompted new phenotypic data.

12. The method of claim 8 further comprising prompting the volunteers to provide new biological samples.

13. The method of claim 8 wherein the secured database is not accessible via the internet.

14. The method of claim 8 wherein the prompting step includes sending email.

15. The method of claim 8 wherein the prompting step includes transmitting a web page.

16. The method of claim 8 wherein the biological sample is a blood sample.

17. The method of claim 8 wherein the biological sample is a hair sample.

18. The method of claim 8 wherein the biological sample is a urine sample.

19. The method of claim 8 wherein the biological sample is a biopsy. sample.

20. The method of claim 8 wherein the biological sample is a skin sample.

21. A secure database system for maintaining genotypic and phenotypic data, the system comprising:

a secure database;

a server coupled with a world wide network of computers, the server configured to host a web site that creates trust of the web site by users;

a secured area of the web site configured to transmit instructions for submitting biological samples;

a module for identifying prospective volunteers from amongst the users of the web site;

a module for inviting the prospective volunteers to submit phenotypic data and biological samples;

a module for populating the secured database with the received phenotypic data from the volunteers;

a module for populating the secured database with the genetic information obtained from received biological samples of the volunteers;

a module for prompting volunteers to provide new phenotypic data; and

a module for receiving the prompted new phenotypic data and populating the secured database with the prompted new phenotypic data.

22. The method of claim 21 wherein the new phenotypic data includes data that adds to data previously submitted.

23. The method of claim 21 wherein the new phenotypic data includes data that modifies data previously submitted.

24. The system of claim 21 further comprising a module for receiving unprompted new phenotypic data via the world wide network of computers and populating the secured database with the unprompted new phenotypic data.

25. The system of claim 21 further comprising a module for prompting the volunteers to provide new biological samples.

26. The system of claim 21 wherein the secured database is not accessible via the internet.

27. The system of claim 21 wherein the module for prompting includes a module for sending e-mail to volunteers.

28. The system of claim 21 wherein the module for prompting includes a module for transmitting a web page to volunteers.