USE OF EXENDINS AND AGONISTS THEREOF FOR THE REDUCTION OF FOOD INTAKE
First Claim
1. A method for treating conditions or disorders which can be alleviated by reducing food intake in a subject comprising administering to said subject a therapeutically effective amount of an exendin or an exendin agonist.
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Accused Products
Abstract
Methods for treating conditions or disorders which can be alleviated by reducing food intake are disclosed which comprise administration of an effective amount of an exendin or an exendin agonist, alone or in conjunction with other compounds or compositions that affect satiety. The methods are useful for treating conditions or disorders, including obesity, Type II diabetes, eating disorders, and insulin-resistance syndrome. The methods are also useful for lowering the plasma glucose level, lowering the plasma lipid level, reducing the cardiac risk, reducing the appetite, and reducing the weight of subjects. Pharmaceutical compositions for use in the methods of the invention are also disclosed.
95 Citations
31 Claims
- 1. A method for treating conditions or disorders which can be alleviated by reducing food intake in a subject comprising administering to said subject a therapeutically effective amount of an exendin or an exendin agonist.
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13. A method for reducing the appetite of a subject comprising administering to said subject an appetite-lowering amount of an exendin or an exendin agonist.
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14. A method for reducing the weight of a subject comprising administering to said subject a therapeutically effective amount of an exendin or an exendin agonist.
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15. A method for lowering plasma lipids comprising administering to said subject a therapeutically effective amount of an exendin or an exendin agonist.
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23. A pharmaceutical composition for use in the treatment of conditions or disorders associated with hypernutrition comprising a therapeutically effective amount of an exendin or exendin agonist in association with a pharmaceutically acceptable carrier.
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28. A pharmaceutical composition for use in reducing the appetite of a subject comprising a therapeutically effective amount of an exendin or exendin agonist in association with a pharmaceutically acceptable carrier.
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29. A pharmaceutical composition for use in reducing the weight of a subject comprising a therapeutically effective amount of an exendin or exendin agonist in association with a pharmaceutically acceptable carrier.
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30. A pharmaceutical composition for use in lowering the plasma lipid level of a subject comprising a therapeutically effective amount of an exendin or exendin agonist in association with a pharmaceutically acceptable carrier.
Specification