Suspension of nanospheres of lipophilic active principle stabilized with water-dispersible polymers
First Claim
1. Stable colloidal suspension consisting essentially:
- of a continuous aqueous phase, of nanospheres of lipophilic active principle with a mean particle size ranging from 0.01 to 1 μ
m, of at least one surfactant, and of colloidal particles, with a mean size ranging from 10 to 500 nm, of at least one water-dispersible polymer.
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Abstract
The present invention relates to a stable colloidal suspension consisting essentially:
of a continuous aqueous phase,
of nanospheres of lipophilic active principle with a mean particle size ranging from 0.01 to 1 μm,
of at least one surfactant, and
of colloidal particles, with a mean size ranging from 10 to 500 nm, of at least one water-dispersible polymer,
and also to topical-application compositions containing such a colloidal suspension.
The invention also relates to the use of water-dispersible polymers in the form of colloidal particles with a mean size ranging from 10 to 500 nm, to stabilize aqueous suspensions of nanospheres of lipophilic active principle, with a mean particle size ranging from 0.01 nm to 1 μm, against the recrystallization of the active principle.
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Citations
31 Claims
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1. Stable colloidal suspension consisting essentially:
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of a continuous aqueous phase, of nanospheres of lipophilic active principle with a mean particle size ranging from 0.01 to 1 μ
m,of at least one surfactant, and of colloidal particles, with a mean size ranging from 10 to 500 nm, of at least one water-dispersible polymer. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 19, 20, 30, 31)
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18. Use of water-dispersible polymers in the form of colloidal particles with a mean size ranging from 10 to 500 nm to stabilize aqueous suspensions of nanospheres of lipophilic active principle, with a mean particle size ranging from 0.01 to 1 μ
- m, against the recrystallization of the active principle.
- View Dependent Claims (21, 22, 23, 24, 25, 26, 27, 28, 29)
Specification