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Viral vectors having reduced virulence

  • US 20020155529A1
  • Filed: 04/19/2001
  • Published: 10/24/2002
  • Est. Priority Date: 04/19/2001
  • Status: Active Grant
First Claim
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1. An expression vector comprising a vaccinia virus having a deletion of the region encoding amino acids 184-190 of the E3L gene product wherein said vector further comprises exogenous DNA operably linked to regulatory elements that control expression of said exogenous DNA.

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