MRI-guided interventional mammary procedures
First Claim
1. A method for an invasive procedure on a breast of a patient comprising:
- a) positioning a breast of a patient between at least two non-magnetically susceptible supports;
b) applying pressure to said breast with said at least two supports;
c) examining said breast with MRI; and
d) inserting and guiding a medical implement into said breast with constant MRI visualization of the inserting and guiding.
1 Assignment
0 Petitions
Accused Products
Abstract
The combination of contrast enhanced magnetic resonance imaging (MRI) and MR-guided subcutaneous core biopsy can be used as a robust approach for the diagnosis and treatment of breast cancer. MRI provides the means to accurately position and monitor interventional procedures such as biopsy, removal of tissue or other transcanular procedures. MRI may also be used in this invention to position and monitor the progress of breast conserving therapies (BCT), such as laser photo-ablation, cryoablation and localized hyperthermia. The general practice of this invention is to provide a remotely controlled apparatus for MR-guided interventional procedures in the breast. The apparatus allows the practice of a method that provides flexibility in conditioning the breast, i.e. orientation and degree of compression, and in setting the trajectory of the intervention. To that end, a robust conditioning/positioning device, fitted with the appropriate degrees of freedom, enhances the efficacy and efficiency of breast interventions by providing the flexibility in planning and executing an appropriate procedure strategy that better suits interventional procedures, either those in current use or yet to be developed. The novelty and potential commercial success of the device originates from its high maneuverability to set and perform the procedure strategy and its adaptability to accommodate an array of interventional probes. Remote control of this device can allow planning the operation and performing the relevant tasks in a short period, for example, within the contrast window provided by a single injection of a contrast agent, and this feature can be operator-independent.
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Citations
56 Claims
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1. A method for an invasive procedure on a breast of a patient comprising:
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a) positioning a breast of a patient between at least two non-magnetically susceptible supports;
b) applying pressure to said breast with said at least two supports;
c) examining said breast with MRI; and
d) inserting and guiding a medical implement into said breast with constant MRI visualization of the inserting and guiding. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50)
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14. A method for an invasive procedure on a breast of a patient comprising:
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positioning a breast of a patient between at least two non-magnetically susceptible supports;
injecting the patient with a contrast agent so that the concentration of the contrast agent within the breast will increase to a maximum concentration for a period of time after injection;
before, during or slightly after the concentration of the contrast agent reaches the maximum concentration, applying pressure to the breast to restrict blood flow within the breast;
maintaining the pressure on the breast to reduce the rate of flow of contrast agent out of the breast; and
examining tissue by a non-invasive procedure of the breast which examining procedure is enhanced by the use of said contrast agent while the rate of blood flow is restricted.
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27. A system comprising:
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a first compression surface;
a second compression surface aligned substantially parallel with the first compression surface wherein the first compression surface and the second compression surface are each positioned along a first axis;
a compression adjuster adapted to adjust a distance between the first compression surface and the second compression surface along the first axis;
a stage coupled to the first compression surface and the second compression surface and adapted to rotate on a second axis substantially orthogonal to the first axis; and
a probe guide having an intervention axis and adapted to guide a probe for insertion into a region between the first compression surface and the second compression surface along the intervention axis.
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51. A system comprising:
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a rotatable platform having a first rotational axis;
a first rigid structure substantially normal with, and coupled to, the platform;
a second rigid structure substantially normal with, and coupled to, the platform;
a compression adjuster coupled to the platform and adapted to adjust a distance between the first rigid structure and the second rigid structure;
a guide, having a guide axis, coupled to the platform and aligned to direct a probe along the guide axis into a region disposed between the first rigid structure and the second rigid structure;
a first remote control coupled to the guide and adapted to adjust an angle between the guide axis and the platform; and
a second remote control coupled to the guide and adapted to adjust a distance between the guide axis and the platform. - View Dependent Claims (52, 53, 54, 55, 56)
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Specification