Over-coated chewing gum formulations
First Claim
1. A method for delivering a medicament to an individual comprising the steps of:
- providing a chewing gum that includes a gum center and a coating that substantially surrounds the center, the coating comprising at least 50% by weight of the chewing gum, the coating including a medicament that is designed to be delivered into the systemic system of the individual; and
chewing the chewing gum causing the medicament to enter the systemic system of the individual through an oral mucosa of the individual.
3 Assignments
0 Petitions
Accused Products
Abstract
Methods and products for delivering a medicament or agent to an individual are provided. The product includes a coating having a medicament or agent. The medicament or agent is present within the coating that surrounds a gum center (the water soluble portion and a water insoluble base portion). By chewing the gum, the medicament or agent is released from the product. Continuing to chew the chewing gum creates a pressure within the buccal cavity forcing the agent or medicament directly into the systemic system of the individual through the oral mucosa contained in the buccal cavity. This greatly enhances the absorption of the drug into the systemic system as well as the bioavailability of the drug within the system.
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Citations
34 Claims
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1. A method for delivering a medicament to an individual comprising the steps of:
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providing a chewing gum that includes a gum center and a coating that substantially surrounds the center, the coating comprising at least 50% by weight of the chewing gum, the coating including a medicament that is designed to be delivered into the systemic system of the individual; and
chewing the chewing gum causing the medicament to enter the systemic system of the individual through an oral mucosa of the individual. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A chewing gum comprising:
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a gum center; and
a coating including a medicament that surrounds the gum center, the coating comprising at least 50% by weight of the chewing gum product, the medicament being designed to be delivered into the systemic system of a patient. - View Dependent Claims (10, 11, 12, 13, 14, 15, 16, 17, 19, 20, 21, 22, 23, 24, 25, 26, 28, 29)
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18. A product including a medicament that is designed to function by being delivered through the systemic system of an individual comprising:
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a chewing gum center; and
a coating that at least substantially surrounds the chewing gum center and includes a medicament and a high-intensity sweetener, the coating comprising at least 50% by weight of the product.
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27. A method of delivering a medicament comprising the steps of:
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providing a chewing gum having a gum center and a coating that substantially surrounds the center, the coating comprising at least 50% by weight of the chewing gum, the coating including a medicament and not including a shellac layer; and
chewing the chewing gum for at least 2 minutes in a buccal cavity of an individual chewing the chewing gum thereby causing the medicament to be absorbed into the systemic system of the individual.
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30. A method for delivering a medicament to the systemic system of an individual comprising the steps of:
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providing a chewing gum product that includes a gum center and a coating having a formulation that includes a medicament, designed to be delivered through the systemic system, and a sufficient amount of a masking agent to provide acceptable organoleptic properties, the formulation comprising at least 50% by weight of the chewing gum product; and
chewing the chewing gum product to cause the medicament to be released from the formulation into the systemic system of the individual through a buccal cavity of the individual. - View Dependent Claims (31, 32, 33, 34)
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Specification