Devices and methods for the release of volatile substances and applications thereof

• US 20020160035A1
• Filed: 02/26/2002
• Published: 10/31/2002
• Est. Priority Date: 02/28/2001
• Status: Abandoned Application

• Current Assignee: Spiros Fotinos
• Original Assignee: Spiros Fotinos
• Inventors: Fotinos, Spiros
• Application Number:
  US10/084,264
• Publication Number:
  US 20020160035A1
• Time in Patent Office: Days
• US Class Current: 424/443
• CPC Class Codes: A01N 2300/00 Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48
• CPC Class Codes: A01N 25/18 Vapour or smoke emitting compositions with delayed or sustained release
• CPC Class Codes: A01N 25/34 Shaped forms, e.g. sheets, not provided for in any other sub-group of this main group
• CPC Class Codes: A01N 65/00 Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof containing compounds of determined constitution A01N27/00 - A01N59/00
• CPC Class Codes: A61K 8/0208 Tissues; Wipes; Patches
• CPC Class Codes: A61K 9/007 Pulmonary tract; Aromatherapy
• CPC Class Codes: A61K 9/7023 Transdermal patches and similar drug-containing composite devices, e.g. cataplasms galenical aspects of iontophoretic devices A61K9/0009; microneedle arrays A61K9/0021; buccal patches A61K9/006
• CPC Class Codes: A61L 9/04 using substances evaporated in the air without heating
• CPC Class Codes: A61L 9/042 with the help of a macromolecular compound as a carrier or diluent A61L9/048 takes precedence
• CPC Class Codes: A61L 9/12 Apparatus, e.g. holders, therefor
• CPC Class Codes: A61Q 13/00 Formulations or additives for perfume preparations essential oils or perfumes per se C11B9/00
• CPC Class Codes: A61Q 17/02 containing insect repellants

Abstract

A patch delivers a volatile substance to an environment. The patch provides the volatile substance within a solid layer positioned between a breathable layer and a barrier layer. A release liner is removably adhered to the barrier layer. The solid layer may be formed by mixing the volatile substance with a liquid agent that forms a solid below 40° C. The liquid mixture is applied to the breathable layer and allowed to solidify. The other layers are added thereto.

Claims

1. A patch, comprising:

a breathable layer;

a barrier layer;

an effective amount of a volatile agent within a solid layer, the solid layer positioned between the breathable layer and the barrier layer, wherein the barrier layer is impermeable to the volatile agent; and

a release liner removably adhered to the barrier layer.

2. A patch according to claim 1, wherein the solid layer is non-hydrophilic.

3. A patch according to claim 1, wherein the solid layer comprises a gelatin mixture.

4. A patch according to claim 1, wherein the solid layer comprises ozokerities wax.

5. A path according to claim 1, wherein the solid layer comprises sodium stearate.

6. A patch according to claim 1, wherein the volatile agent is released from the patch over a period of at least six hours.

7. A patch according to claim 1, wherein the volatile agent is an aromatherapy oil.

8. A patch according to claim 1, wherein the volatile agent is an insect repellant.

9. A patch according to claim 1, wherein the volatile agent is a deodorant.

10. A patch according to claim 1, wherein the volatile agent is a perfume.

11. A patch according to claim 1, wherein the volatile agent has a therapeutic effect of reducing sinus congestion.

12. A patch according to claim 1, wherein the volatile agent has a sedative effect.

13. A path according to claim 1, wherein the volatile agent has a mood altering effect.

15. A method according to claim 14, further comprising packaging the patch within a sealed pouch for removal therefrom prior to application of the patch to a surface of a subject.

16. A method according to claim 14, wherein the solid further comprises any of a gelatin, a wax or sodium stearate.

17. A method according to claim 14, wherein the volatile substance is selected from an aromatherapy oil, an insect repellant, a deodorant, a perfume or an agent with therapeutic activity.

18. A method according to claim 14, wherein the volatile substance has a therapeutic activity selected from reducing sinus congestion, having a sedative activity and having a mood altering activity.

19. A method of delivering a volatile substance to an environment from a surface location of a subject, comprising applying a patch of claim 1 adhesively to the surface location of the subject so as to deliver the volatile substance to the environment.

20. A method of delivering a volatile substance to an environment from a surface location of a subject, comprising applying a patch manufactured according to claim 14, adhesively to the surface location of the subject so as to deliver the volatile substance to the environment

21. A method according to claim 19 or 20, wherein the volatile substance is selected from an aromatherapy oil, an insect repellant, a deodorant, a perfume or an agent with therapeutic activity.

22. A method according to claim 19 or 20, wherein the volatile substance has a therapeutic activity selected from reducing sinus congestion, having a sedative activity and having a mood altering activity.

14. A method of making a patch for release of volatile substances, comprising:

mixing a volatile substance with a liquid agent, wherein the agent forms a solid below 40°

C. and is capable of forming a liquid above 45°

C. and below 90°

C.;

applying the liquid mixture of step(a) onto a breathable layer and permitting the liquid to form a solid;

preparing a barrier layer for adhesive attachment to the breathable layer and solid;

laminating the barrier layer by adhesion to the solid and the breathable layer; and

laminating a release liner by adhesion to the barrier layer.