Microfluidic sedimentation
First Claim
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1. A microfluidic device comprising:
- a microfluidic structure having an inlet and a sedimentation region;
a fluid containing particles having a density different from that of said fluid;
and means for moving said fluid through said inlet into said sedimentation region such that a concentration gradient of said particle is established across the vertical dimension of said sedimentation region.
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Abstract
A device for promoting sedimentation within microfluidic channels which uses gravity to separate particles from fluid. Particles such as blood cells or beads are separated from a carrier fluid using gravity combined with various devices such as membranes and sonic energy in different embodiments.
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Citations
6 Claims
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1. A microfluidic device comprising:
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a microfluidic structure having an inlet and a sedimentation region;
a fluid containing particles having a density different from that of said fluid;
and means for moving said fluid through said inlet into said sedimentation region such that a concentration gradient of said particle is established across the vertical dimension of said sedimentation region.
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2. A microfluidic device, comprising:
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a microfluidic channel having a depth and a width, and an inlet and a first and a second outlet, with first outlet placed higher than said second outlet with respect to the vertical axis of said microfluidic channel;
and a fluid containing particles that have a different density from the fluid flowing through said channel such that said particles exit said channel preferentially through said first or said second outlet.
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3. A microfluidic device, comprising:
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a first channel and a second channel;
means for preventing solid material from moving from said first channel to said second channel, said means being located between said first channel and said second channel to form a collection of solid particles located in said first channel;
and means for moving a fluid through said first and said second channel such that said fluid interacts with said particles located in said first channel. - View Dependent Claims (4, 5, 6)
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Specification