Novel human transporter proteins and polynucleotides encoding the same

• US 20020164627A1
• Filed: 03/06/2002
• Published: 11/07/2002
• Est. Priority Date: 03/12/2001
• Status: Abandoned Application

• Current Assignee: Lexicon Genetics, Incorporated
• Original Assignee: Lexicon Genetics, Incorporated
• Inventors: Hu, Yi, Wilganowski, Nathaniel L., Burnett, Michael B., Nepomnichy, Boris
• Application Number:
  US10/091,628
• Publication Number:
  US 20020164627A1
• Time in Patent Office: Days
• US Class Current: 435/6
• CPC Class Codes: C07K 14/47 from mammals

Abstract

Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.

Claims

1. An isolated nucleic acid molecule comprising at least 59 contiguous nucleotides from SEQ ID NO:

1.

2. An isolated nucleic acid molecule comprising a nucleotide sequence that:

(a) encodes the amino acid sequence shown in SEQ ID NO;

2; and

(b) hybridizes under stringent conditions to the nucleotide sequence of SEQ ID NO;

1 or the complement thereof.

3. An isolated nucleic acid molecule comprising a nucleotide sequence that encodes the amino acid sequence shown in SEQ ID NO:

2.

4. A substantially isolated protein having the transporter activity of the protein shown in SEQ ID NO:

2, which is encoded by a nucleotide sequence that hybridizes to SEQ ID NO;

1 under highly stringent conditions.

5. A substantially isolated protein according to claim 4 comprising the amino acid sequence of SEQ ID NO:

2.

6. An isolated nucleic acid molecule comprising at least 47 contiguous nucleotides from SEQ ID NO:

4.

7. An isolated nucleic acid molecule comprising a nucleotide sequence that:

(a) encodes the amino acid sequence shown in SEQ ID NO;

5; and

(b) hybridizes under stringent conditions to the nucleotide sequence of SEQ ID NO;

4 or the complement thereof.

8. An isolated nucleic acid molecule comprising a nucleotide sequence that encodes the amino acid sequence shown in SEQ ID NO:

4.

9. A substantially isolated protein having the transporter activity of the protein shown in SEQ ID NO:

5, which is encoded by a nucleotide sequence that hybridizes to SEQ ID NO;

4 under highly stringent conditions.

10. A substantially isolated protein according to claim 9 comprising the amino acid sequence of SEQ ID NO:

5.