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Method and system for evaluating and locating cardiac ischemia

  • US 20020165459A1
  • Filed: 12/26/2001
  • Published: 11/07/2002
  • Est. Priority Date: 06/26/2000
  • Status: Active Grant
First Claim
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1. A method of assessing cardiac ischemia in a subject to provide a measure of cardiac or cardiovascular health in that subject, said method comprising the steps of:

  • (a) collecting a first RR-interval data set from said subject during a stage of gradually increasing heart rate;

    (b) collecting a second RR-interval data set from said subject during a stage of gradually decreasing heart rate, with said first and second RR-interval data sets being collected while minimizing the influence of rapid transients due to autonomic nervous system and hormonal influence on said data sets;

    (c) comparing said first RR-interval data set to said second RR-interval data set to determine the difference between said data sets; and

    (d) generating from said comparison of step (c) a measure of cardiac ischemia during stimulation in said subject, wherein a greater difference between said first and second data sets indicates greater cardiac ischemia and lesser cardiac or cardiovascular health in said subject;

    wherein said first and second RR-interval data sets are collected from a plurality of separate electrode leads, and wherein said generating step includes the step of generating an indication of the location of cardiac ischemia in said subject.

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