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Patterned polymer synthesis

  • US 20020168669A1
  • Filed: 03/26/2002
  • Published: 11/14/2002
  • Est. Priority Date: 03/26/2001
  • Status: Abandoned Application
First Claim
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1. A method of constructing a nucleic acid array, the method comprising:

  • determining a plurality of layer maps from a set of nucleic acid sequences, each layer map corresponding to a particular register and indicating discrete addresses at which corresponding nucleic acid subunits are to be coupled;

    for each register, directing a plurality of applicator units that each are supplied with a different nucleic acid subunit to each transfer the respective nucleic acid subunit to a substrate at the discrete addresses indicated by the layer map for the respective nucleic acid subunit;

    coupling the transferred nucleic acid subunits to a reactive terminus to form an array of nucleic acids.

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