APPARATUS AND METHOD FOR DISEASE DETECTION
First Claim
1. A method for detecting presence of a diseased state, comprising:
- a. obtaining a specimen;
b. preparing a sample from the specimen;
c. irradiating the sample;
d. obtaining at least one of absorption and emission spectra from the irradiated sample; and
e. analyzing the at least one of the absorption and emission spectra to determine the presence of the diseased state.
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Accused Products
Abstract
The present invention relates to an apparatus and method for disease detection. The apparatus and method use a radiation source to irradiate a sample. An analyzer measures the absorption and/or emission spectra from the sample to detect the presence of the disease state in the sample. In this regard, a comparator may compare the measured spectra with the spectrum of a control. Analysis of the parameters of the spectra including, but not limited to, peak intensity wavelength, amplitude at the peak intensity, area ratio of left and right portions of the emission spectra, and shifts of the peak intensity wavelength, allows determination of HIV infection, Hepatitis A, B and C, and other diseases. Selective absorbents, such as C-M Affi Gel Blue and activated charcoal, may be used to treat the samples before measurements, which is found to improve discrimination of diseased and non-diseased samples. The present invention is capable of detecting HIV infection at a stage when it is still undetectable by conventional diagnosis methods.
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Citations
24 Claims
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1. A method for detecting presence of a diseased state, comprising:
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a. obtaining a specimen;
b. preparing a sample from the specimen;
c. irradiating the sample;
d. obtaining at least one of absorption and emission spectra from the irradiated sample; and
e. analyzing the at least one of the absorption and emission spectra to determine the presence of the diseased state.
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2. A method for detecting presence of an infection, comprising:
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a. obtaining a specimen;
b. preparing a sample from the specimen;
c. irradiating the sample;
d. obtaining at least one of absorption and emission spectra from the irradiated sample; and
e. analyzing the at least one of the absorption and emission spectra to determine the presence of the infection.
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3. A method for detecting presence of an infection, comprising:
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a. obtaining a specimen;
b. preparing a sample from the specimen;
c. irradiating the sample;
d. obtaining at least one of absorption and emission spectra from the irradiated sample; and
e. analyzing the at least one of absorption and emission spectra to determine variation of the at least one of the absorption and emission spectra from a spectrum characteristic of a non-infected state to detect the presence of the infection.
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4. A method comprising:
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a. preparing a sample from an organism;
b. irradiating the sample;
c. obtaining at least one of absorption and emission spectra from the irradiated sample; and
d. analyzing the at least one of the absorption and emission spectra to determine the state of health of the organism.
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5. An apparatus for detecting presence of a diseased state in a sample, comprising:
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a. radiation source; and
b. analyzer operatively associated with the sample for measuring at least one of absorption and emission spectra from the sample to detect the presence of the diseased state in the sample. - View Dependent Claims (6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23)
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24. An apparatus for detecting presence of a diseased state, comprising:
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a. means for irradiating the sample;
b. means for obtaining at least one of absorption and emission spectra from the irradiated sample; and
c. means for analyzing the at least one of the absorption and emission spectra to determine the presence of the diseased state.
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Specification