Optimal method and apparatus for neural modulation for the treatment of neurological disease, particularly movement disorders
First Claim
1. A neural modulation system for use in treating disease which provides stimulus intensity which may be varied.
6 Assignments
0 Petitions
Accused Products
Abstract
A neurological control system for modulating activity of any component or structure comprising the entirety or portion of the nervous system, or any structure interfaced thereto, generally referred to herein as a “nervous system component.” The neurological control system generates neural modulation signals delivered to a nervous system component through one or more intracranial (IC) stimulating electrodes in accordance with treatment parameters. Such treatment parameters may be derived from a neural response to previously delivered neural modulation signals sensed by one or more sensors, each configured to sense a particular characteristic indicative of a neurological or psychiatric condition. Neural modulation signals include any control signal which enhances or inhibits cell activity. Significantly the neurological control system considers neural response, in the form of the sensory feedback, as an indication of neurological disease state and/or responsiveness to therapy, in the determination of treatment parameters.
221 Citations
45 Claims
- 1. A neural modulation system for use in treating disease which provides stimulus intensity which may be varied.
-
28. A neurological control system for modulating the activity of at least one nervous system component, the neurological control system comprising:
-
at least one intracranial stimulating electrode, each constructed and arranged to deliver a neural modulation signal to at least one nervous system component;
at least one sensor, each constructed and arranged to sense at least one parameter, including but not limited to physiologic values and neural signals, which is indicative of at least one of disease state, magnitude of symptoms, and response to therapy; and
a stimulating and recording unit constructed and arranged to generate said neural modulation signal based upon a neural response sensed by said at least one sensor in response to a previously delivered neural modulation signal.
-
-
35. An apparatus for modulating the activity of at least one nervous system component, said system comprising:
-
means for delivering neural modulation signal to said nervous system component; and
means for sensing neural response to said neural modulation signal.
-
Specification