Method for reducing or preventing transplant rejection in the eye and intraocular implants for usetherefor
First Claim
Patent Images
1. A method for preventing transplant rejection in an eye of an individual, comprising:
- a) performing an ocular transplant procedure; and
b) implanting in the eye a bioerodible drug delivery system comprising an immunosuppressive agent and a bioerodible polymer.
6 Assignments
0 Petitions
Accused Products
Abstract
Methods for reducing or preventing transplant rejection in the eye of an individual are described, comprising: a) performing an ocular transplant procedure; and b) implanting in the eye a bioerodible drug delivery system comprising an immunosuppressive agent and a bioerodible polymer.
-
Citations
45 Claims
-
1. A method for preventing transplant rejection in an eye of an individual, comprising:
-
a) performing an ocular transplant procedure; and
b) implanting in the eye a bioerodible drug delivery system comprising an immunosuppressive agent and a bioerodible polymer. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 19)
-
-
17. A method for preventing transplant rejection in the eye of an individual, comprising:
-
a) performing an ocular transplant procedure; and
b) implanting a solid body into the eye, said body comprising particles of an immunosuppressive agent entrapped within a bioerodible polymer, whereby said agent is released from the body by erosion of the polymer.
-
-
18. A kit for preventing transplant rejection in the eye, comprising:
-
a) a bioerodible drug delivery system comprising an immunosuppressive agent and a bioerodible polymer, wherein the drug delivery system is designed to be implanted in the eye; and
b) instructions for use.
-
-
20. A method comprising
a) performing a retinal pigment epithelium transplant or a cornea transplant on an eye of an individual; - and
b) placing in the eye a bioerodible drug delivery system comprising dexamethasone or cyclosporin A and a bioerodible polymer. - View Dependent Claims (21, 22, 23, 24, 25, 26, 27, 28, 29)
- and
-
30. A method comprising placing in an eye of an individual a bioerodible drug delivery system;
-
wherein the bioerodible drug delivery system includes an immunosuppressive agent and a bioerodible polymer; and
wherein the eye of the individual has undergone or is undergoing an ocular transplant procedure. - View Dependent Claims (31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45)
-
Specification