Use of melatonin for treating androgenetic and diffuse alopecia

• US 20020183377A1
• Filed: 05/30/2002
• Published: 12/05/2002
• Est. Priority Date: 11/30/1999
• Status: Abandoned Application

• Current Assignee: Asat Ag Applied Science & Technology
• Original Assignee: Asat Ag Applied Science & Technology
• Inventors: Elsner, Peter
• Application Number:
  US10/130,297
• Publication Number:
  US 20020183377A1
• Time in Patent Office: Days
• US Class Current: 514/415
• CPC Class Codes: A61K 31/4045 Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
• CPC Class Codes: A61K 8/492 having condensed rings, e.g. indol
• CPC Class Codes: A61P 17/14 for baldness or alopecia
• CPC Class Codes: A61P 5/26 Androgens
• CPC Class Codes: A61P 5/28 Antiandrogens
• CPC Class Codes: A61Q 7/00 Preparations for affecting hair growth

Abstract

The invention relates to the use of melatonin and melatonin-containing preparations for the treatment of androgenetic and diffuse alopecia of the female type.

Claims

1. The use of melatonin for producing a composition for the treatment of androgenetic and diffuse alopecia of the female type.

2. The use as claimed in claim 1, wherein the composition can be applied topically.

3. The use as claimed in claim 1 or 2, wherein the composition can be applied as a spray, solution, lotion, cream or ointment.

4. The use as claimed in one of the preceding claims, wherein the melatonin preparation has an active compound concentration of 0.001 to 1% (wt/wt).

5. The use as claimed in one of the preceding claims, wherein the amount of the composition applied daily contains an active compound dose of 0.01 to 10 mg per day.

6. The use as claimed in one of the preceding claims, wherein a reduction in the telogenic rate is achieved.

7. The use as claimed in one of the preceding claims, wherein an increase in the anagenic rate is achieved.

8. The use as claimed in one of the preceding claims, wherein an enlargement of the hair diameter and/or an increase in the breaking force of the hair is achieved.

9. The use of melatonin for producing a composition for enlarging the hair diameter and/or increasing the stretching ability in the case of diffuse alopecia.

10. The use as claimed in claim 9. in the case of occipital hair.

11. The use as claimed in claim 9 or 10 in female patients.