Method for computing visual performance from objective ocular aberration measurements

• US 20020186346A1
• Filed: 04/04/2002
• Published: 12/12/2002
• Est. Priority Date: 10/20/2000
• Status: Active Grant

• Current Assignee: AMO Development LLC (Johnson & Johnson)
• Original Assignee: Amo Wavefront Sciences LLC (Johnson & Johnson)
• Inventors: Rammage, Ron, Stantz, Keith, Neal, Daniel R.
• Granted Patent: US 6,607,274 B2
• Time in Patent Office: Days
• US Class Current: 351/205
• CPC Class Codes: A61B 3/0025 characterised by electronic signal processing, e.g. eye models

Abstract

A method for computing the visual performance of a human or animal subject based on objective measurements of visual refraction, including higher order aberrations, includes measuring wavefront aberrations of a subject ocular pupil, computing a point-spread-function from the measured pupil aberration, providing a test image, and convolving the test image with the point-spread-function. A simulated image may be produced from the convolution result of the test image with the point-spread-function. One or more specific terms of the point-spread-function may be subtracted therefrom prior to the convolving step to simulate an effect of a correcting means, such as spectacles lenses, contact lenses, or laser surgery. A best correction for a given subject may be determined by adjusting the terms that are subtracted to optimize the resultant image.

Claims

1. A method for computing the visual performance of a human or animal subject based on objective measurements of visual refraction including higher order aberrations, comprising the steps of:

measuring wavefront aberrations of a subject ocular pupil;

computing a point-spread-function from the measured pupil aberration;

providing a test image; and

convolving the test image with the point-spread-function.

2. The method of claim 1 wherein the wavefront aberrations are measured with an objective aberrometer.

3. The method of claim 1 wherein the wavefront aberrations are measured with one selected from a group consisting of a Shack-Hartmann wavefront sensor system, a Tscherning aberrometer, a scanning resolved refractometer, and a Moire deflectometer.

4. The method of claim 1 where the wavefront aberrations are measured objectively by projecting a beam of light onto a retina and analyzing resulting return images.

5. The method of claim 1, further comprising producing a simulated image from a convolution result of convolving the test image with the point-spread-function.

6. The method of claim 1 wherein the test image is a Snellen acuity chart, and further comprising producing a simulated subject view of the Snellen acuity chart from a convolution result of convolving the Snellen acuity chart with the point-spread-function.

7. The method of claim 1 wherein convolving the test image with the point-spread-function comprises the steps of:

performing an inverse Fourier transform of a modulus squared of the point-spread-function to compute an optical transfer function;

computing a Fourier transform of the test image; and

computing an inverse Fourier transform of a product of the optical transfer function and the test image Fourier transform.

8. The method of claim 7, wherein the Fourier transform and inverse Fourier transforms are computed with Fast Fourier Transforms.

9. A method for computing a point-spread-function of a human or animal ocular system from objective aberrometry measurements, comprising the steps of:

measuring a pupil aberration function with an objective aberrometer;

arid

computing the point-spread-function as a modulus squared of a Fourier transform of the measured pupil aberration function.

10. A method for determining a visual acuity of an ocular optical system, comprising:

measuring a pupil aberration function with an objective aberrometer;

computing a point-spread-function as a modulus squared of a Fourier transform of the measured pupil aberration function; and

analyzing a spatial extent of the point-spread-function.

11. A method for determining Snellen acuity from evaluation of a double object when convolved with a point-spread-function, comprising the steps of:

measuring a subject pupil aberration function with an objective aberrometer;

computing a point-spread-function from the modified pupil aberration function;

computing an Optical Transfer Function (OTF) from the computed point-spread-function;

providing an input image which consists of appropriate targets coded so that known image features can be correlated to a visual acuity number; and

convolving the input image with the point-spread-function by multiplying a Fourier transform of the input image by the OTF and then performing an inverse Fourier transform.

12. The method of claim 11 where the double object is a series of bars with different orientations.

14. The method of claim 13, wherein adjusting the specific term comprises subtracting the specific term from the point-spread-function.

16. The method of claim 15 wherein the corrective means is spectacle lenses.

17. The method of claim 15 wherein the corrective means is contact lenses.

18. The method of claim 15 wherein the corrective means is laser refractive surgery.

19. The method of claim 15 wherein the corrective means is Laser Thermal Keratotomy.

20. The method of claim 15, wherein the corrective means includes one selected from a group consisting of Interocular lenses, femto-second laser correction, and corneal implants.

13. A method for computing an image, comprising the steps of:

measuring wavefront aberrations of a subject ocular pupil;

computing a point-spread-function from the measured pupil aberration;

providing a test image;

convolving the test image with the point-spread-function; and

producing a simulated image from a convolution result of convolving the test image with the point-spread-function,

wherein at least one specific term of the point-spread-function is adjusted prior to the convolving step to simulate an effect of a correcting means.

15. A method for computing an effect of corrective means on a subject'"'"'s visual acuity, comprising the steps of:

measuring a subject pupil aberration function with an objective aberrometer;

adjusting terms in the measured subject pupil aberration function that correspond to specific corrective means, producing a modified pupil aberration function;

computing a point-spread-function from the modified pupil aberration function;

computing an optical transfer function (OTF) of the computed point-spread-function;

multiplying a Fourier transform of a test image by the OTF to produce a Fourier result; and

performing an inverse Fourier transform on the Fourier result.

21. A method of determining a best correction for a given subject, comprising the steps of:

measuring a subject pupil aberration function with an objective aberrometer;

subtracting terms from the pupil aberration function that correspond to specific corrective means, producing a modified pupil aberration function;

computing a point-spread-function from the modified pupil aberration function;

computing an optical transfer function (OTF) of the computed point-spread-function;

multiplying a Fourier transform of a test image by the OTF to produce a Fourier result;

performing an inverse Fourier transform on the Fourier result; and

adjusting the terms that are subtracted to optimize a resultant image.