Method and apparatus for non-invasive analysis of blood glucose
First Claim
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1. An apparatus for substantially noise-free transmission of an Rf signal comprising:
- (a) a plurality of spaced-apart permanent magnets that generate a magnetic field;
(b) at least one transmission node, and at least one reflection node spaced apart from the transmission node with a gap therebetween, that are disposed within the magnetic field, the transmission and reflection nodes comprised of an electrically-conductive material; and
(c) a source that generates an Rf signal having a selected frequency spectrum that is connected to the transmission node and reflection node, such that a detectable Rf signal is received by the reflection node.
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Abstract
The present invention provides apparatus for non-invasive detection and quantitation of analytes in a sample, such as blood glucose. The apparatus employs a novel amplifier that uses high-gauss permanent magnets (12, 14) to permit an Rf signal to be transmitted through the sample (116). The concentration of the analyte can be determined from the magnitude of the reduction in the amplitude of the Rf signal at a characteristic frequency.
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Citations
17 Claims
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1. An apparatus for substantially noise-free transmission of an Rf signal comprising:
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(a) a plurality of spaced-apart permanent magnets that generate a magnetic field;
(b) at least one transmission node, and at least one reflection node spaced apart from the transmission node with a gap therebetween, that are disposed within the magnetic field, the transmission and reflection nodes comprised of an electrically-conductive material; and
(c) a source that generates an Rf signal having a selected frequency spectrum that is connected to the transmission node and reflection node, such that a detectable Rf signal is received by the reflection node. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 17)
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15. A method of causing an Rf signal to be transmitted between spaced-apart transmission and reflection nodes, the method comprising:
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(a) providing at least one transmission node, and at least one reflection node spaced apart from the transmission node with a gap therebetween, the transmission and reflection nodes comprised of an electrically-conductive material, and, connected to the transmission node and a reflection node, a source that generates an Rf signal having a selected frequency spectrum;
(b) disposing the transmission node and the reflecting node in a magnetic field produced by a plurality of spaced-apart high gauss permanent magets.
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16. A method for detecting an analyte in a sample comprising:
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(a) providing an apparatus comprising (i) a plurality of spaced-apart permanent magnets that generate a magnetic field;
(ii) at least one transmission node, and at least one reflection node spaced apart from the transmission node with a gap therebetween, that are disposed within the magnetic field, the transmission and reflection nodes comprised of an electrically-conductive material;
(iii) a source that generates an Rf signal having a selected frequency spectrum that is connected to the transmission node and reflection node; and
(iv) an analyzer connected to the transmission node and reflection node;
(b) disposing a sample comprising an analyte between the transmission node and reflection node; and
(c) using the analyzer to detect a reduction in the amplitude of the Rf signal at a frequency that is characteristic of the presence of the analyte.
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Specification