Systems to promote dissolution of thrombi in the thoracic cavity
First Claim
1. A system for treating a thoracic cavity comprising an ultrasound applicator adapted to be coupled to an electric signal generating machine to generate ultrasound energy, the ultrasound applicator being sized to be placed to the chest of an individual to transcutaneously apply ultrasound energy to the thoracic cavity, and an agent administered to the individual to promote dissolution of thrombi before, during, or after application of the ultrasound energy, the agent being selected from a group consisting essentially of a thrombolytic agent, an anticoagulant, an antiplatelet drug, a fibrinolytic drug, or aspirin, or combinations thereof, or in combination with one or more thrombolytic agents, or microbubbles, or microparticles.
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Accused Products
Abstract
Systems and methods initiate and maintain treatment of a reduced blood perfusion incident using ultrasound in a clinical location or a non-clinical, even mobile location, outside a traditional medical setting. The systems and methods make possible a therapeutic ultrasound treatment modality that “follows the patient” while outside the medical center, while en route to the medical center, and even while being transported within the medical center itself. The systems and methods also make possible therapeutic ultrasound treatment modalities for a traditional medical setting, including cardiac rehabilitation centers, and for in-home use.
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Citations
67 Claims
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1. A system for treating a thoracic cavity comprising
an ultrasound applicator adapted to be coupled to an electric signal generating machine to generate ultrasound energy, the ultrasound applicator being sized to be placed to the chest of an individual to transcutaneously apply ultrasound energy to the thoracic cavity, and an agent administered to the individual to promote dissolution of thrombi before, during, or after application of the ultrasound energy, the agent being selected from a group consisting essentially of a thrombolytic agent, an anticoagulant, an antiplatelet drug, a fibrinolytic drug, or aspirin, or combinations thereof, or in combination with one or more thrombolytic agents, or microbubbles, or microparticles.
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17. A system for treating a thoracic cavity comprising
an ultrasound applicator adapted to be coupled to an electric signal generating machine to generate ultrasound energy, the ultrasound applicator being sized to be placed to the chest of the individual to transcutaneously apply ultrasound energy to the thoracic cavity, an assembly worn on the chest and affixed to the ultrasound applicator, to stabilize placement of the ultrasound applicator on the chest during application of ultrasound energy to the thoracic cavity, and an agent administered to the individual to promote dissolution of thrombi before, during, or after application of the ultrasound energy.
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38. A system for treating the thoracic cavity of an individual while being transported comprising
an electric signal generating machine sized to be transported with the individual, an ultrasound applicator adapted to be coupled to the electric signal generating machine to generate ultrasound energy, the ultrasound applicator being sized to be placed to the chest of the individual while being transported to transcutaneously apply ultrasound energy to the thoracic cavity, and an agent administered to the individual to promote dissolution of thrombi before, during, or after application of the ultrasound energy.
Specification
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Current AssigneeTIMI 3 Systems Incorporated
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Original AssigneeTIMI 3 Systems Incorporated
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InventorsThompson, Todd A., Horzewski, Michael J., Low, Mark S.
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Application NumberUS10/034,833Publication NumberTime in Patent OfficeDaysField of SearchUS Class Current601/2CPC Class CodesA61B 2017/00725 Calibration or performance ...A61B 2017/00734 battery operatedA61B 2018/00023 closed, i.e. without wound ...A61B 90/50 Supports for surgical instr...A61N 7/00 Ultrasound therapy lithotri...
