System and method for automatically selecting electrode polarity during sensing and stimulation

• US 20020193834A1
• Filed: 04/12/2001
• Published: 12/19/2002
• Est. Priority Date: 04/12/2001
• Status: Active Grant

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories)
• Inventors: Levine, Paul A.
• Granted Patent: US 6,477,417 B1
• Time in Patent Office: Days
• US Class Current: 607/9
• CPC Class Codes: A61N 1/3627 for treating a mechanical deficiency of the heart, e.g. congestive heart failure or cardiomyopathy
• CPC Class Codes: A61N 1/368 comprising more than one electrode co-operating with different heart regions A61N1/3622, A61N1/3627 take precedence
• CPC Class Codes: A61N 1/3684 for stimulating the heart at multiple sites of the ventricle or the atrium
• CPC Class Codes: A61N 1/36843 Bi-ventricular stimulation
• CPC Class Codes: A61N 1/3918 characterised by shock pathway, e.g. by electrode configuration

Abstract

An implantable multi-chamber cardiac stimulation device includes flexibly programmable electrode stimulation configurations, and is capable of precisely controlling the stimulation sequence between multiple sites. The stimulation device provides a plurality of connection ports that allow independent connection of each electrical lead associated with a particular stimulation site in the heart. Each connection port further provides a unique terminal for making electrical contact with only one electrode such that no two electrodes are required to be electrically coupled. Furthermore, each electrode, whether residing on a unipolar, bipolar or multipolar lead, may be selectively connected or disconnected through programmable switching circuitry that determines the electrode configurations to be used for sensing and for stimulating at each stimulation site. The stimulation device allows for the programmable selection of each electrode terminal connection to a relatively positive or negative battery potential. In this way, each electrode, when electrically connected, may be programmed to act as the cathode or as the anode during sensing or stimulation delivery. Thus, directionality of the depolarization wave may be controlled by programming the cathode and anode assignments of the stimulation electrodes.

Claims

1. A method of automatically selecting sensing or stimulation polarities of a plurality of sensing and stimulation electrodes that are positioned in multiple cardiac chambers, for use with a multi-site cardiac stimulation device, the method comprising the steps of:

defining a plurality of sensing electrode configurations and a plurality of stimulation electrode configurations;

detecting the presence of a cardiac signal in any one of the multiple cardiac chambers with a sensing electrode configuration that corresponds to a first sensing electrode positioned in a right cardiac chamber and a second sensing electrode positioned in a left cardiac chamber;

selectively delivering a stimulus, on demand, to a cardiac chamber with a stimulation electrode configuration that corresponds to a first stimulation electrode positioned in a right cardiac chamber and a second stimulation electrode positioned in a left cardiac chamber; and

independently selecting the polarities of the first sensing electrode, the second sensing electrode, the first stimulation electrode, and the second stimulation electrode.

2. The method of claim 1, further including switching the polarities of the first sensing electrode and the second sensing electrode.

3. The method of claim 1, further including switching the polarities of the first stimulation electrode and the second stimulation electrode.

4. The method of claim 2, further including switching the polarities of the first stimulation electrode and the second stimulation electrode in response to the step of switching the polarities of the first sensing electrode and the second sensing electrode.

5. The method of claim 1, wherein the step of selectively delivering the stimulus includes delivering the stimulus by means of the first and second sensing electrodes.

6. The method of claim 5, wherein the step of selectively delivering the stimulus includes delivering the stimulus by means of at least a third sensing electrode that is different from the first and second sensing electrodes.

7. The method of claim 1, further including controlling a directionality of a depolarization wave by selecting a cathodic assignment and an anodic assignment of the first and second stimulation electrodes.

8. A multi-site cardiac stimulation device capable of automatically selecting sensing or stimulation polarities of a plurality of sensing and stimulation electrodes that are positioned in multiple cardiac chambers, from among a plurality of sensing electrode configurations and a plurality of stimulation electrode configurations, the stimulation device comprising:

a discriminator, coupled to the plurality of sensing electrodes and to the plurality of stimulation electrodes, that detects the presence of a cardiac signal in any one of the multiple cardiac chambers with a sensing electrode configuration that corresponds to a first sensing electrode positioned in a right cardiac chamber and a second sensing electrode positioned in a left cardiac chamber;

a pulse generator, connected to the stimulation electrodes, to selectively deliver a stimulus, on demand, to a cardiac chamber with a stimulation electrode configuration that corresponds to a first stimulation electrode positioned in a right cardiac chamber and a second stimulation electrode positioned in a left cardiac chamber; and

control circuitry, connected to the sensing electrodes, the stimulation electrodes, the pulse generator, and the discriminator to independently select the polarities of the first sensing electrode, the second sensing electrode, the first stimulation electrode, and the second stimulation electrode.

9. The stimulation device of claim 8, wherein the control circuitry includes a programmable switching system that switches the polarities of the first sensing electrode and the second sensing electrode.

10. The stimulation device of claim 8, wherein the control circuitry includes a programmable switching system that switches the polarities of the first stimulation electrode and the second s timulation electrode.

11. The stimulation device of claim 9, wherein the switching system that switches the polarities of the first stimulation electrode and the second stimulation electrode in response to a switch in the polarities of the first sensing electrode and the second sensing electrode.

12. The stimulation device of claim 8, wherein the pulse generator delivers the stimulus by means of the first and second sensing electrodes.

13. The stimulation device of claim 8, wherein the pulse generator delivers the stimulus by means of at least a third sensing electrode that is different from the first and second sensing electrodes.

14. The stimulation device of claim 8, wherein the sensing electrode configuration includes any of a right ventricular or left ventricular unipolar sensing configuration.

15. The stimulation device of claim 8, wherein the sensing electrode configuration includes any of a right atrial unipolar or left atrial sensing configuration.

16. The stimulation device of claim 8, wherein the sensing electrode configuration includes a cross-chamber sensing configuration.

17. The stimulation device of claim 8, wherein the stimulation electrode configuration includes any of a right ventricular or left ventricular unipolar stimulation configuration.

18. The stimulation device of claim 8, wherein the stimulation electrode configuration includes any of a right atrial unipolar or left atrial stimulation configuration.

19. The stimulation device of claim 8, wherein the stimulation electrode configuration includes a cross-chamber stimulation configuration.

20. The stimulation device of claim 8, wherein the sensing electrode configuration includes any one or more of:

a right ventricular or left ventricular unipolar sensing configuration;

a right atrial unipolar or left atrial sensing configuration;

or a cross-chamber sensing configuration; and

wherein the stimulation electrode configuration includes any one or more of;

a right ventricular or left ventricular unipolar stimulation configuration;

a right atrial unipolar or left atrial stimulation configuration;

or a cross-chamber stimulation configuration.

21. A multi-site cardiac stimulation device capable of automatically selecting sensing or stimulation polarities of a plurality of sensing and stimulation electrodes that are positioned in multiple cardiac chambers, the stimulation device comprising:

means for detecting the presence of a cardiac signal with a sensing electrode configuration;

means for selectively delivering a stimulus, on demand, to a cardiac chamber with a stimulation electrode configuration;

means for independently selecting the polarities of the sensing electrodes and the stimulation electrodes;

means for switching the polarities of the sensing electrodes on demand; and

means for switching the polarities of the stimulation electrodes on demand.

22. The stimulation device of claim 21, wherein the sensing electrode configuration includes any one or more of:

a right ventricular or left ventricular unipolar sensing configuration;

a right atrial unipolar or left atrial sensing configuration;

or a cross-chamber sensing configuration; and

wherein the stimulation electrode configuration includes any one or more of;

a right ventricular or left ventricular unipolar stimulation configuration;

a right atrial unipolar or left atrial stimulation configuration;

or a cross-chamber stimulation configuration.