Method for preventing and treating skin aging

• US 20020197286A1
• Filed: 12/05/2001
• Published: 12/26/2002
• Est. Priority Date: 01/16/2001
• Status: Abandoned Application

• Current Assignee: Galen (Chemicals) Ltd. (Abbvie Incorporated)
• Original Assignee: Galen (Chemicals) Ltd. (Abbvie Incorporated)
• Inventors: Brandman, Jane, Hanley, Rochelle
• Application Number:
  US10/007,158
• Publication Number:
  US 20020197286A1
• Time in Patent Office: Days
• US Class Current: 424/401
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 31/565 not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
• CPC Class Codes: A61K 31/567 substituted in position 17 alpha, e.g. mestranol, norethandrolone
• CPC Class Codes: A61P 17/00 Drugs for dermatological disorders
• CPC Class Codes: A61P 17/10 Anti-acne agents
• CPC Class Codes: A61P 17/16 Emollients or protectives, e.g. against radiation

Abstract

Skin aging and acne are prevented and treated with a composition comprising an estrogen and a progestin.

Claims

1. A method for delaying the onset and treating skin aging in a patient in need of treatment comprising administering an effective amount of an estrogen together with a progestogen.

2. A method for delaying the onset and treating skin aging in a patient in need of treatment comprising administering an effective amount of a fixed quantity of a synthetic estrogen in combination with a synthetic progestin.

3. A method for delaying the onset and treating skin aging in a patient in need of treatment comprising administering an effective amount of a fixed quantity of norethindrone acetate (NA) and ethinyl estradiol (EE).

4. A method for delaying the onset and treating skin aging in a patient in need of treatment comprising administering an effective amount of compositions containing 1 mg NA and 5 μ

g EE.

5. A method for delaying the onset and treating skin aging in a patient in need of treatment comprising administering an effective amount of 1 mg NA and 10 μ

g BE in a pharmaceutically acceptable carrier.

6. A method for preventing and treating acne in a patient in need of treatment comprising administering an effective amount of a composition comprising an estrogen and a progestogen.

7. A method for treating and preventing acne in a patient in need of treatment comprising administering an effective amount of a synthetic estrogen in combination with a synthetic progestin.

8. A method for treating and preventing acne in a patient in need of treatment comprising administering an effective amount of NA in combination with EE.

9. A method of preventing and treating acne in a patient in need of treatment comprising administering an effective amount of 1 mg NA and a gradually increasing dose of EE;

20 mcg×

5 days, 30 mcg×

7 days and 35 mcg×

9 days.

10. A method of claim 9 wherein acne is acne vulgaris or cystic acne.

11. A method of preventing and treating acne in a patient in need of treatment comprising administering an effective amount of Estrostep.

12. A method of claim 11 wherein the acne is acne vulgaris or cystic acne.