Capillary array-based sample screening
First Claim
1. A capillary for screening a sample, wherein the capillary is adapted for being held in an array of capillaries, the capillary comprising:
- a first wall defining a lumen for retaining the sample, wherein the first wall forms a waveguide for propagating detectable signals therein; and
a second wall formed of a filtering material, for filtering excitation energy provided to the lumen to excite the sample.
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Abstract
A sample screening platform, system and method for screening and recovery of detectable samples. The platform includes a capillary array including a plurality of capillaries. Each capillary includes at least one wall defining a lumen for retaining the detectable sample. The detectable sample is introduced to and retained in the lumen by capillary forces. In a method of incubating the sample, a second liquid is introduced into the capillary containing the sample. A detection and recovery system includes an optical system for detecting the sample, and a recovery mechanism adapted to contact a capillary containing the sample. The recovery mechanism is further adapted to recover the sample from the capillary, and expel the recovered sample for analysis.
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Citations
10 Claims
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1. A capillary for screening a sample, wherein the capillary is adapted for being held in an array of capillaries, the capillary comprising:
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a first wall defining a lumen for retaining the sample, wherein the first wall forms a waveguide for propagating detectable signals therein; and
a second wall formed of a filtering material, for filtering excitation energy provided to the lumen to excite the sample. - View Dependent Claims (2, 3, 4)
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5. A capillary array for screening a plurality of samples, comprising:
a plurality of capillaries, held together into the array, wherein each capillary includes a first wall defining a lumen for retaining the sample, and a second wall circumscribing the first wall, for filtering excitation energy provided to the lumen to excite the sample. - View Dependent Claims (6, 7, 8, 9, 10)
Specification