Bioactive polymer vaso-occlusive device
First Claim
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1. A non-metal vaso-occlusive device for implantation into the vasculature of a patient to occlude abnormal blood flow comprising:
- a material comprising a polymer or combination of polymers in a solid form, wherein the material is configured in a pre-implantation shape before implantation and assumes a vaso-occluding shape after implantation.
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Abstract
Methods and apparatus for performing vaso-occlusion. The apparatus includes a vaso-occlusion device made of a non-metal material. The non-metal can be one or more polymers, and one or more of the polymers can biodegrade. The device can also comprise a bioactive agent and a radio pacifier. The device can be delivered as a solid or as a liquid injectable material. The methods provide a treatment for abnormal blood flow by implanting such a device at the site of abnormal blood flow. Additionally, is provided methods of making the vaso-occlusive devices.
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Citations
47 Claims
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1. A non-metal vaso-occlusive device for implantation into the vasculature of a patient to occlude abnormal blood flow comprising:
a material comprising a polymer or combination of polymers in a solid form, wherein the material is configured in a pre-implantation shape before implantation and assumes a vaso-occluding shape after implantation. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 15, 16, 17, 18, 19, 20, 21)
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14. A vaso-occlusive device for implantation into the vasculature of a patient to occlude abnormal blood flow comprising:
a liquid injectable polymer or combination of polymers for delivery to a site of abnormal blood flow upon which delivery the polymer polymerizes or precipitates to assume a vaso-occluding solid shape that occludes abnormal blood flow.
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22. A method of treating a patient having abnormal blood flow comprising:
implanting into the vasculature of the patient at the site of abnormal blood flow a material comprising a polymer or combination of polymers, wherein the material is either a liquid injectable that polymerizes to a solid or precipitates as a solid upon placement in the patient or is a solid material configured in a pre-implantation shape before implantation and changes to a vaso-occluding shape after implantation. - View Dependent Claims (23, 24, 25, 26, 27, 28, 30, 31, 32, 33, 34, 35, 36, 37, 38, 40, 41, 42, 43, 44, 45, 46, 47)
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29. A method of making a vaso-occlusive device for occluding abnormal blood flow comprised of a non-metal solid material comprising:
configuring the non-metal material into a pre-implantation shape, wherein upon implantation into a patient at a site of abnormal blood flow the material assumes a vaso-occluding shape.
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39. A method of making a vaso-occlusive device for occluding abnormal blood flow in a patient comprising:
providing a liquid injectable polymer material that polymerizes to a solid or precipitates to a solid upon placement in the patient.
Specification