Delivery of muscle relaxants through an inhalation route
First Claim
1. An aerosol for inhalation therapy, wherein the aerosol comprises particles comprising at least 10 percent by weight of a muscle relaxant.
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Abstract
The present invention relates to the delivery of muscle relaxants through an inhalation route. Specifically, it relates to aerosols containing a muscle relaxant that is used in inhalation therapy. In a composition aspect of the present invention, the aerosol comprises particles comprising at least 5 percent by weight of muscle relaxant. In a method aspect of the present invention, a muscle relaxant is delivered to a mammal through an inhalation route. The method comprises: a) heating a composition, wherein the composition comprises at least 5 percent by weight of a muscle relaxant, to form a vapor; and, b) allowing the vapor to cool, thereby forming a condensation aerosol comprising particles, which is inhaled by the mammal. In a kit aspect of the present invention, a kit for delivering a muscle relaxant through an inhalation route to a mammal is provided which comprises: a) a composition comprising at least 5 percent by weight of a muscle relaxant; and, b) a device that forms a muscle relaxant containing aerosol from the composition, for inhalation by the mammal.
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Citations
15 Claims
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1. An aerosol for inhalation therapy, wherein the aerosol comprises particles comprising at least 10 percent by weight of a muscle relaxant.
- 2. An aerosol for inhalation therapy, wherein the aerosol comprises particles comprising at least 10 percent by weight of quinine, chlorzoxazone, carisprodol or cyclobenzaprine.
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8. A method of delivering quinine, chlorzoxazone, carisprodol or cyclobenzaprine to a mammal through an inhalation route, wherein the route comprises:
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a) heating a composition, wherein the composition comprises at least 5 percent by weight of quinine, chlorzoxazone, carisprodol or cyclobenzaprine, to form a vapor; and
,b) allowing the vapor to cool, thereby forming a condensation aerosol comprising particles, which is inhaled by the mammal. - View Dependent Claims (9, 10, 11, 12, 13, 14)
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15. A kit for delivering quinine, chlorzoxazone, carisprodol or cyclobenzaprine through an inhalation route to a mammal, wherein the kit comprises:
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a) a composition comprising at least 5 percent by weight of quinine, chlorzoxazone, carisprodol or cyclobenzaprine; and
,b) a device that forms a quinine, chlorzoxazone, carisprodol or cyclobenzaprine aerosol from the composition, for inhalation by the mammal and wherein the device comprises;
a) an element for heating the quinine, chlorzoxazone, carisprodol or cyclobenzaprine composition to form a vapor;
b) an element allowing the vapor to cool to form an aerosol; and
,c) an element permitting the mammal to inhale the aerosol.
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Specification