Methods for increasing the survival of neuronal cells
First Claim
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1. A method of increasing the survival of dopamine secreting cells, comprising the steps of administering a retinoid X receptor (RXR) ligand to dopamine secreting cells in an amount sufficient for the RXR ligand to bind RXR and increase the survival of the dopamine secreting cells.
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Abstract
The invention relates to methods of increasing the survival of dopamine secreting cells, comprising the steps of administering a retinoid X receptor (RXR) ligand to dopamine secreting cells, wherein the binding of the RXR ligand increases the survival of the dopamine secreting cells. Therapeutic approaches to neurodegenerative diseases are also disclosed.
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24 Claims
- 1. A method of increasing the survival of dopamine secreting cells, comprising the steps of administering a retinoid X receptor (RXR) ligand to dopamine secreting cells in an amount sufficient for the RXR ligand to bind RXR and increase the survival of the dopamine secreting cells.
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12. A method of increasing the survival of dopamine-secreting cells in a subject in need thereof, comprising the steps of administering a retinoid X receptor (RXR) ligand to the subject, in an amount sufficient for the RXR ligand to bind RXR and increase the survival of the dopamine-secreting cells.
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