Drive system for an infusion pump

• US 20030009133A1
• Filed: 04/12/2002
• Published: 01/09/2003
• Est. Priority Date: 04/13/2001
• Status: Active Grant

• Current Assignee: Trividia Healthcare Systems, LLC
• Original Assignee: Nipro Diabetes Systems, Inc. (Nipro Corporation)
• Inventors: Ramey, Kirk
• Granted Patent: US 6,854,620 B2
• Time in Patent Office: Days
• US Class Current: 604/155
• CPC Class Codes: A61M 2005/14264 with means for compensating influence from the environment
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/1456 with a replaceable reservoir comprising a piston rod to be moved into the reservoir, e.g. the piston rod is part of the removable reservoir
• CPC Class Codes: A61M 5/16831 Monitoring, detecting, signalling or eliminating infusion flow anomalies low-level float-valves causing cut-off A61M5/40; indicating or recording presence, absence or direction of flow in general G01P13/0066
• CPC Class Codes: A61M 5/16854 by monitoring line pressure

Abstract

A pump system for an infusion system includes a linear drive (36, 36′) which minimizes the space occupied by the pump components in a portable housing (10, 10′). A motor (34) and a motor drive shaft (42) are arranged in parallel with, and adjacent to a syringe (14, 14′) and lead screw (94, 94′). A gear box (54) connects the drive shaft and lead screw to transfer rotational movements between them. A piston driving member, such as a cone (116) or drive nut (116′) converts the rotational movement of the lead screw into linear motion of a syringe piston (24). Sensors (150, 152) detect when the piston or cone is in a “home” position and in an “end” position, respectively. Optionally, a proximity sensor (170) is used to ensure that the cone and the piston (24) are abutting during dispensing. Alternatively, a clamping member (350) selectively clamps the lead screw (94′) against linear motion in at least a dispensing direction.

Claims

1. A liquid delivery system comprising:

a housing which accommodates a syringe containing the liquid;

a motor carried by the housing;

a drive system, operatively connected with the motor, which advances a piston of the syringe to expel liquid from a barrel of the syringe, the drive system including;

a threaded rotatable shaft; and

a piston drive member, which linearly advances the piston, the drive member defining a threaded portion which engage threads of the shaft, the piston drive member advancing linearly as the shaft rotates.

2. The liquid delivery system of claim 1, wherein the drive member defines an engagement portion which selectively engages an engagement portion of the piston.

3. The liquid delivery system of claim 1, wherein the drive member engagement portion defines threads which threadably engage corresponding threads of the piston engagement portion.

4. The liquid delivery system of claim 1, wherein the drive system includes a rotatable gear and the shaft defines a fitting configured for selective coupling with the gear.

5. The liquid delivery system of claim 4, wherein one of the fitting and the rotatable gear defines a cavity configured for sliding receipt of a pin on the other of the fitting and the gear, the pin and the cavity having surfaces which contact each other causing the fitting to rotate as the gear rotates.

6. The liquid delivery system of claim 4, further including a clamping member which selectively clamps the shaft against linear advancement, relative to the housing, in at least a dispensing direction, while permitting the shaft to rotate relative thereto.

7. The liquid delivery system of claim 6, wherein the clamping member includes:

a post which defines a slot for receiving the shaft therein; and

a biasing member which biases the post to an engaged position, in which the slot receives the shaft.

8. The liquid delivery system of claim 7, wherein the biasing member includes a spring.

9. The liquid delivery system of claim 7, further including a stop which, when actuated, allows the post to move from a disengaged position, in which the slot is spaced from the shaft, to the engaged position, in which the slot receives the shaft.

10. The liquid delivery system of claim 1, wherein the housing defines an opening for receiving the syringe therethrough, the opening defining threads for engaging threads on the syringe barrel to lock the syringe to the housing.

11. The liquid delivery system of claim 1, wherein the piston drive member includes a portion which is received within the piston.

12. The liquid delivery system of claim 1, wherein the piston drive member includes a flange which abuts a flange of the piston during advancement of the piston.

13. The liquid delivery system of claim 1, further including:

a proximity sensor which senses occurrence of at least one of two states;

(a) the piston drive member abutting the piston, and

(b) the piston drive member not abutting the piston;

a microprocessor which receives a signal from the proximity sensor and alerts a user of the delivery system of the occurrence of at least one of state (a) and state (b).

14. The liquid delivery system of claim 13, wherein the piston drive member defines a first flange and the piston defines a second flange, at least a portion of the proximity sensor being associated with at least one of the first and second flanges.

15. The liquid delivery system of claim 13, wherein the microprocessor alerts the user by actuating an alarm when state (b) occurs.

16. The liquid delivery system of claim 13, wherein the proximity sensor includes at least one of:

(a) a contact switch which is located on an abutting surface of one of the piston drive member and the piston; and

(b) a first electrically conductive member on a surface one of the piston drive member and the piston and a second electrically conductive member on a surface of the other of the piston drive member and the piston, such that current flows between the first and second electrically conductive members when the surfaces are abutting.

17. The liquid delivery system of claim 1, further including:

a first position sensor which detects when at least one of the piston and the piston drive member is in a first position; and

a second position sensor which detects when the at least one of the piston and the piston drive member is in a second position, linearly spaced from the first position.

18. The liquid delivery system of claim 17, wherein when the at least one of the piston and the piston drive member is in the first position, the piston is spaced from a liquid outlet of the syringe through which the liquid is dispensed and wherein when the at least one of the piston and the piston drive member is in the second position, the piston is closely adjacent the liquid outlet of the syringe.

19. The liquid delivery system of claim 1, wherein the motor is a stepper motor and further including:

an encoder which detects step movements of the motor; and

an occlusion sensor which detects when there is an occlusion in the delivery system, the occlusion sensor receiving signals from the encoder and determining an occlusion from a reduction in a speed of the step movements.

20. The liquid delivery system of claim 1, further including a cap, which selectively connects the syringe to the housing, the cap including:

a first threaded portion which threadably engages a threaded portion on the syringe; and

a second threaded portion which threadably engages a threaded portion on the housing.

21. The liquid delivery system of claim 1, further including:

a guide element, mounted to the housing, which inhibits rotation of the piston drive member during linear advancement of the piston drive member.

22. An infusion system comprising:

a housing which receives a cartridge, the housing defining an opening for receiving the cartridge therethrough;

a threaded shaft which is selectively drivingly coupled with a piston of the cartridge, the threaded shaft linearly advancing the piston as the shaft rotates to expel a liquid from a barrel of the cartridge; and

a clamping member which is selectively actuated to engage the shaft and thereby inhibit linear advancement of the shaft, relative to the barrel.

23. The infusion system of claim 22, wherein the clamping member includes a slotted portion which defines a slot configured to receive a portion of the shaft therein and the shaft includes first and second spaced projections which abut the slotted portion when the clamping member is in an engaged position in which the slot receives the shaft portion.

24. The system of claim 22, wherein the shaft is removable from the housing with the cartridge.

25. The infusion system of claim 22, wherein, the housing opening defines threads for releasably engaging corresponding threads on the cartridge.

27. The method of claim 26, further including, after step (a):

(d) coupling the rotatable shaft with a drive system which rotates the shaft during step (c).

28. The method of claim 27, wherein step (d) includes:

inserting the piston, drive member, and shaft into a housing which houses the drive system.

29. The method of claim 27, wherein step (b) includes:

moving the clamping means from a first position, in which the clamping means is spaced from the shaft, to a second position, in which the clamping means engages the shaft.

26. A method of dispensing a liquid from a barrel of a cassette having a piston, comprising:

(a) coupling a piston drive member to the piston, the piston drive member carrying a rotatable shaft;

(b) actuating a clamping means which clamps the shaft against linear motion in a dispensing direction;

(c) after step b, rotating the shaft to advance the piston drive member and the piston to dispense the fluid from the barrel.

30. A method of dispensing a medicament from a cartridge including a barrel which receives a piston comprising:

(a) bringing a piston drive member and the piston into an abutting relationship in a first position;

(b) sensing that the piston drive member is in the first position and sending a signal to a controller;

(c) advancing the piston drive member incrementally under the control of the controller to advance the piston to dispense the fluid from the barrel until the piston drive member is in a second position linearly spaced from the first position; and

(d) sensing that the piston drive member is in the second position and sending a signal to a controller.

31. The method of claim 30, further including, after step (d), the controller arresting advancement of the piston drive member.