Electrokinetic delivery of medicaments
First Claim
1. An electrokinetic delivery system for personal use in self-administration of a medicament to a treatment site on an individual, comprising:
- a device for releasable securement to an individual'"'"'s finger and shaped in part to conform to at least a portion of the individual'"'"'s finger;
at least one of an electrically conductive medicament or a medicament with an electrically conductive carrier therefor;
a retainer for releasably securing the device to the individual'"'"'s finger;
a self-contained power source carried by said device;
a first electrode carried by said device adjacent a distal end portion thereof and adjacent the tip of the individual'"'"'s finger upon retention of the device on the individual'"'"'s finger, said first electrode being in electrical contact with said power source;
a second electrode carried by said device for electrical contact with a portion of the individual'"'"'s finger, said second electrode being in electrical contact with said power source whereby, upon application of said first electrode to a treatment site with said at least one medicament interposed between the first electrode and the treatment site and completion of an electrical circuit through the first electrode, the at least one medicament, the treatment site, the individual'"'"'s body, said second electrode and said power source, said device causes an electrical current to flow for electrokinetically driving the at least one medicament into the treatment site.
8 Assignments
0 Petitions
Accused Products
Abstract
An electrokinetic delivery or diagnostic device for personal use and self-administration of a medicament to a treatment site is provided. The device includes a housing containing a power supply, a first active electrode and a ground tactile electrode. An applicator includes a pad for containing medicament for overlying the first electrode of the device. The medicament may be applied by the user to the pad, contained within the pad or contained in rupturable capsules within the pad, together with a hydrogel if necessary for imparting electrical conductivity whereby, upon application of the applicator to the treatment site, the medicament is electrokinetically transported into the treatment site. In another form, the applicator is self-contained, having a power supply, a first electrode overlying a pad and a ground electrode from the opposite side from the pad whereby the individual presses the pad against the treatment site to complete the electrical circuit and electrokinetically drive the medicament into the treatment site.
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Citations
147 Claims
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1. An electrokinetic delivery system for personal use in self-administration of a medicament to a treatment site on an individual, comprising:
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a device for releasable securement to an individual'"'"'s finger and shaped in part to conform to at least a portion of the individual'"'"'s finger;
at least one of an electrically conductive medicament or a medicament with an electrically conductive carrier therefor;
a retainer for releasably securing the device to the individual'"'"'s finger;
a self-contained power source carried by said device;
a first electrode carried by said device adjacent a distal end portion thereof and adjacent the tip of the individual'"'"'s finger upon retention of the device on the individual'"'"'s finger, said first electrode being in electrical contact with said power source;
a second electrode carried by said device for electrical contact with a portion of the individual'"'"'s finger, said second electrode being in electrical contact with said power source whereby, upon application of said first electrode to a treatment site with said at least one medicament interposed between the first electrode and the treatment site and completion of an electrical circuit through the first electrode, the at least one medicament, the treatment site, the individual'"'"'s body, said second electrode and said power source, said device causes an electrical current to flow for electrokinetically driving the at least one medicament into the treatment site. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49)
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50. A method of treatment by electrokinetic self-administration of a medicament into a treatment site for an individual, comprising:
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providing a device shaped in part to conform to at least a portion of an individual'"'"'s finger and having a self-contained power source, first and second electrodes, and a substrate in electrical contact with said first electrode and having an exposed contact surface;
providing at least one of an electrokinetically transportable medicament or a medicament with an electrically conductive carrier therefor;
releasably retaining the device on the individual'"'"'s finger, with the second electrode in electrical contact with the individual'"'"'s finger;
providing said at least one medicament in contact with said substrate or the treatment site;
while the device remains retained on the individual'"'"'s finger, placing the contact surface of said substrate into contact with the individual'"'"'s treatment site and causing electrical current to flow through said first electrode, the electrically transportable medicament or the conductive carrier, the treatment site, the individual'"'"'s body, said second electrode and said power source to electrokinetically drive the medicament into the treatment site. - View Dependent Claims (51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98)
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- 99. A delivery device for self-administration of a substance to a treatment site on an individual, comprising a self-contained disposable applicator including a pad for containing the substance, a power supply, a first electrode overlying said pad and electrically connected to said power supply and a second electrode having a tactile surface in electrical contact with said power supply and lying on a side of said applicator remote from said pad, said second electrode having an electrically conductive material overlying the tactile surface, whereby, upon the individual'"'"'s hand or a portion thereof in contact with said tactile surface of said second electrode holding the applicator pad against the treatment site, an electrical circuit is completed between the first electrode through the treatment site and the second electrode via the tactile surface, the electrically conductive material and the individual'"'"'s hand and body for electrokinetically driving the substance into the treatment site.
Specification