Delivery of antiemetics through an inhalation route
First Claim
1. An aerosol for inhalation therapy, wherein the aerosol comprises particles comprising at least 10 percent by weight of an antiemetic.
2 Assignments
0 Petitions
Accused Products
Abstract
The present invention relates to the delivery of antiemetics through an inhalation route. Specifically, it relates to aerosols containing antiemetics that are used in inhalation therapy. In a composition aspect of the present invention, the aerosol comprises particles comprising at least 5 percent by weight of an antiemetic. In a method aspect of the present invention, an antiemetic is delivered to a mammal through an inhalation route. The method comprises: a) heating a composition, wherein the composition comprises at least 5 percent by weight of an antiemetic, to form a vapor; and, b) allowing the vapor to cool, thereby forming a condensation aerosol comprising particles, which is inhaled by the mammal. In a kit aspect of the present invention, a kit for delivering an antiemetic through an inhalation route to a mammal is provided which comprises: a) a composition comprising at least 5 percent by weight of an antiemetic; and, b) a device that forms an antiemetic aerosol from the composition, for inhalation by the mammal.
76 Citations
15 Claims
-
1. An aerosol for inhalation therapy, wherein the aerosol comprises particles comprising at least 10 percent by weight of an antiemetic.
- 2. An aerosol for inhalation therapy, wherein the aerosol comprises particles comprising at least 10 percent by weight of dolasetron, granisetron, or metoclopramide.
-
8. A method of delivering dolasetron, granisetron, or metoclopramide to a mammal through an inhalation route, wherein the route comprises:
-
a) heating a composition, wherein the composition comprises at least 5 percent by weight of dolasetron, granisetron, or metoclopramide, to form a vapor; and
,b) allowing the vapor to cool, thereby forming a condensation aerosol comprising particles, which is inhaled by the mammal. - View Dependent Claims (9, 10, 11, 12, 13, 14)
-
-
15. A kit for delivering dolasetron, granisetron or metoclopramide through an inhalation route to a mammal, wherein the kit comprises:
-
a) a composition comprising at least 5 percent by weight of dolasetron, granisetron or metoclopramide; and
,b) a device that forms a dolasetron, granisetron or metoclopramide aerosol from the composition, for inhalation by the mammal and wherein the device comprises;
a) an element for heating the dolasetron, granisetron or metoclopramide composition to form a vapor;
b) an element allowing the vapor to cool to form an aerosol; and
,c) an element permitting the mammal to inhale the aerosol.
-
Specification