Pulse oximetry method and system with improved motion correction

• US 20030028086A1
• Filed: 08/12/2002
• Published: 02/06/2003
• Est. Priority Date: 09/29/2000
• Status: Active Grant

• Current Assignee: Datex-Ohmeda Incorporated (General Electric Company)
• Original Assignee: Datex-Ohmeda Incorporated (General Electric Company)
• Inventors: Heckel, Donald W.
• Granted Patent: US 6,839,582 B2
• Time in Patent Office: Days
• US Class Current: 600/323
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/7207 of noise induced by motion artifacts

Abstract

A pulse oximetry method and system for improved motion correction is disclosed. The method/system provides for the use of a detector output signal to obtain a different plurality of differential absorption data sets in corresponding relation to each of a succession of measurement, wherein each of the data sets includes differential absorption values for light of a first wavelength and light of a second wavelength. The data sets are processed to obtain a relative motion estimate value for each measurement. When the relative motion estimate value for a given measurement falls within a predetermined range (i.e., corresponding with clinical motion), a corresponding blood analyte indicator value is adjusted in a predetermined manner, wherein the corresponding adjusted blood analyte indicator is employable to obtain at least one blood analyte concentration value. In one embodiment, blood analyte indicator values may be readily multiplied by a predetermined adjustment factor (i.e., when clinical motion is identified). The relative motion estimate value for a given measurement may be obtained by conducting a principal component analysis of the corresponding plurality of data sets relative to a corresponding best fit function therefor to obtain corresponding variance values V₁, V₂. The variance value V₁, and/or V₂ for a given current measurement may be employed to obtain a current motion estimate value. The current motion estimate value and the relative motion estimate value obtained for a prior low motion measurement (i.e., for which no adjustment was necessary) may be used to compute the relative motion estimate value for the current measurement. The variance values V₁ and/or V₂ are also employable to compute an ongoing, updated motion probability factor, wherein such factor may be used to adjust relative motion estimates values in instances of rapid tissue perfusion changes.

Claims

1. A method for use in a pulse oximetry system which provides a detector output indicative of light absorption by a tissue-under-test at each of a plurality of different light wavelengths and which employs the detector output to compute blood analyte indicator values for each of a plurality of measurements, said method comprising the steps of:

utilizing said detector output to obtain a corresponding relative motion estimate value for each of said plurality of measurements; and

, determining;

(i) whether the corresponding relative motion estimate value for each of said plurality of measurements is within a first predetermined range, wherein for each measurement having a corresponding relative motion estimate value within the first predetermined range the corresponding blood analyte indicator value is adjusted in a first adjustment manner, and wherein said adjusted blood analyte indicator value is employable to obtain at least one blood analyte concentration value;

(ii) whether the relative motion estimate value corresponding with each of said plurality of measurements is within a second predetermined range, non-overlapping with said first predetermined range, wherein for each measurement having a corresponding relative motion estimate value within said second predetermined range the corresponding blood analyte indicator value is employable to obtain at least one blood analyte concentration value without adjustment to the corresponding blood analyte indicator value; and

(iii) whether the relative motion estimate value corresponding with each of said plurality of measurements is within a third predetermined range, non-overlapping with said first and second predetermined ranges, wherein for each measurement having a corresponding relative motion estimate value within the third predetermined range a previously determined blood analyte indicator value corresponding to a measurement within said first or second predetermined ranges is adjusted in a second adjustment manner different from said first adjustment manner, and

wherein said adjusted previously determined blood analyte indicator value is employable to obtain at least one blood analyte concentration value.

6. The method of claim 1 wherein, for each measurement having a corresponding relative motion estimate value within the first predetermined range, said first adjustment manner includes:

adjusting the corresponding blood analyte indicator value utilizing a predetermined adjustment factor.

7. The method of claim 6 wherein said adjusting step includes:

multiplying the corresponding blood analyte indicator value by said predetermined adjustment factor.

8. The method of claim 7, wherein said adjusting step further includes:

comparing the corresponding blood analyte indicator value to a predetermined threshold value, wherein said predetermined adjustment factor is scaled when said blood analyte indicator value exceeds said predetermined threshold value.

9. The method of claim 7, wherein said predetermined adjustment factor is set to a value between about 0.5 and 0.85.

2. The method of claim 2 wherein, for each measurement having a corresponding relative motion estimate value within the third predetermined range, said second adjustment manner includes:

adjusting the previously determined blood analyte indicator value utilizing an adjustment factor.

3. The method of claim 2 further comprising:

utilizing said detector output signal to obtain moving average values of total tissue absorption of AC and DC signal components corresponding with each of said plurality of different light wavelengths, wherein said moving average values are determined for each of said plurality of measurements;

computing a first ratio of the moving average values obtained for the measurement corresponding to the previously determined blood analyte indicator value;

computing a second ratio of the moving average values obtained for the measurement having a corresponding relative motion estimate value within the third predetermined range; and

computing the adjustment factor by dividing the first ratio by the second ratio to obtain a result and multiplying the result by a constant.

4. The method of claim 3 wherein said adjusting step includes:

multiplying the previously determined blood analyte indicator value by the adjustment factor.

5. The method of claim 3 wherein in said step of utilizing said detector output signal to obtain moving average values, a predetermined number of the measurements are utilized.

10. A method for use in a pulse oximetry system which provides a detector output indicative of light absorption by a tissue-under-test at each of a plurality of different light wavelengths and which employs the detector output to compute blood analyte indicator values for each of a plurality of measurements, said method comprising the steps of:

utilizing said detector output to obtain a corresponding relative motion estimate value for each of said plurality of measurements; and

,

determining whether the relative motion estimate value corresponding with each of said plurality of measurements is within a predetermined range; and

adjusting, for each measurement having a corresponding relative motion estimate value within the third predetermined range, a previously determined blood analyte indicator value corresponding to a measurement outside said predetermined range, wherein said adjusted previously determined blood analyte indicator value is employable to obtain at least one blood analyte concentration value.

11. The method of claim 10 wherein said adjusting step includes:

multiplying the previously determined blood analyte indicator value by an adjustment factor.

12. The method of claim 11 further comprising:

utilizing said detector output signal to obtain moving average values of total tissue absorption of AC and DC signal components corresponding with each of said plurality of different light wavelengths, wherein said moving average values are determined for each of said plurality of measurements;

computing a first ratio of the moving average values obtained for the measurement corresponding to the previously determined blood analyte indicator value;

computing a second ratio of the moving average values obtained for the measurement having a corresponding relative motion estimate value within the third predetermined range; and

computing the adjustment factor by dividing the first ratio by the second ratio to obtain a result and multiplying the result by a constant.

13. The method of claim 12 wherein in said step of utilizing said detector output signal to obtain moving average values, a predetermined number of the measurements are utilized.