Topical delivery of L-arginine to cause beneficial effects
First Claim
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1. A method of increasing localized bloodflow in tissues to increase growth rate and repair of cells by comprising the steps of:
- selecting a substance from the group consisting of L-arginine and L-arginine derivatives;
applying topically to the skin a delivery vehicle for the substance, said delivery vehicle containing an effective amount of the substance of at least 5% to 50% by weight wherein bloodflow is increased promoting healing.
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Abstract
The application of L-arginine and its derivatives to the skin causes beneficial effects of wound healing, increasing erectile function and increased growth of hair when applied in sufficient quantity to the skin. A hostile biophysical agent may be combined with the L-arginine to increase its absorption into the skin. The desired concentrations of the hostile biophysical agent is increased when concentration of L-arginine is less than 20% of the concentration of the substance applied to maximize its effect.
91 Citations
15 Claims
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1. A method of increasing localized bloodflow in tissues to increase growth rate and repair of cells by comprising the steps of:
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selecting a substance from the group consisting of L-arginine and L-arginine derivatives;
applying topically to the skin a delivery vehicle for the substance, said delivery vehicle containing an effective amount of the substance of at least 5% to 50% by weight wherein bloodflow is increased promoting healing. - View Dependent Claims (2, 3, 4, 5)
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6. A topical compound for application to the skin to cause beneficial effects comprising:
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a substance selected from the group consisting of L-arginine and L-arginine derivatives having a concentration of 5 to 35%;
an ion donor capable of causing a hostile biophysical environment, wherein the ion donor is an ionic salt selected from the group consisting of sodium chloride, choline chloride, potassium chloride, lithium chloride and magnesium chloride and mixtures thereof which causes the substance to migrate from the delivery vehicle to the skin where the substance is absorbed by tissue wherein the ionic salt is 5% to 80% by weight. - View Dependent Claims (7, 8)
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9. A method of treating impotence in a male comprising:
delivering a substance selected from the group consisting of L-arginine and L-arginine derivatives to the penis by topically applying to the penis a delivery vehicle for the substance, said delivery vehicle containing an effective amount of the substance of at least 5% to 35% by weight wherein penile function is enhanced through increased bloodflow. - View Dependent Claims (10, 11)
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12. A method of promoting hair growth comprising:
delivering a substance selected from a group consisting of L-arginine and L-arginine derivatives, wherein a selected area of the skin where hair growth is desired by topically applying to the selected area of skin where hair growth is desired a delivery vehicle for the substance, said delivery vehicle containing an effective amount of the substance of at least 5% to 35% by weight. - View Dependent Claims (13, 14, 15)
Specification