System and method for cardiac rhythm management with dynamically adjusted synchronized chamber pacing protection period

• US 20030028222A1
• Filed: 06/14/2002
• Published: 02/06/2003
• Est. Priority Date: 12/26/2000
• Status: Active Grant

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Stahmann, Jeffrey E.
• Granted Patent: US 7,003,347 B2
• Time in Patent Office: Days
• US Class Current: 607/9
• CPC Class Codes: A61N 1/3627 for treating a mechanical deficiency of the heart, e.g. congestive heart failure or cardiomyopathy
• CPC Class Codes: A61N 1/3684 for stimulating the heart at multiple sites of the ventricle or the atrium
• CPC Class Codes: A61N 1/36843 Bi-ventricular stimulation

Abstract

A device and method for cardiac rhythm management in which one heart chamber, designated as the synchronized chamber, is paced in accordance with a pacing mode that employs sense signals from the opposite chamber, designated as the rate chamber. A synchronized chamber protection period triggered by an intrinsic or paced beat in the synchronized chamber is used to inhibit pacing without otherwise disturbing the pacing algorithm. The duration of the synchronized chamber protection period is dynamically adjusted based upon detection of a repolarization in the synchronized chamber

Claims

1. A cardiac rhythm management device, comprising:

sensing channels for sensing intrinsic depolarizations in heart chambers designated as a rate chamber and a synchronized chamber and generating sense signals in accordance therewith;

a controller for controlling the delivery of paces in accordance with a programmed pacing mode;

wherein the controller is programmed to pace the synchronized chamber in accordance with a synchronized pacing mode based upon rate chamber events and wherein pacing of the synchronized chamber is inhibited during a synchronized chamber protection period that is initiated by a synchronized chamber sense or pace; and

,

wherein the controller is further programmed to adjust the duration of the synchronized chamber protection period based upon detection of a repolarization in the synchronized chamber.

2. The device of claim 1 wherein the controller is programmed to adjust the synchronized chamber protection period by setting it to approximately equal a measured depolarization interval in the synchronized chamber, the depolarization interval starting with a depolarization in the synchronized chamber and ending with a detected repolarization.

3. The device of claim 2 wherein the controller is programmed to classify measured depolarization intervals as to type depending upon whether the depolarization is due to a sense or pace in the synchronized chamber, with the synchronized chamber protection period being set during each cardiac cycle to approximately equal an appropriate measured depolarization interval in accordance with whether the synchronized protection period is initiated by a sense or a pace.

4. The device of claim 2 wherein the controller is programmed to classify measured depolarization intervals as to type depending upon a measured heart rate, with the synchronized chamber protection period being set during each cardiac cycle to approximately equal a measured depolarization interval whose type corresponds with a presently measured heart rate.

5. The device of claim 2 wherein the controller is programmed to periodically measure depolarization intervals used for setting the synchronized chamber protection period.

6. The device of claim 2 wherein the controller is programmed to average a plurality of measured depolarization intervals.

7. The device of claim 2 wherein the controller is programmed to:

classify measured depolarization intervals as to type depending upon whether the depolarization is due to a sense or pace in the synchronized chamber, with the synchronized chamber protection period being set during each cardiac cycle to approximately equal an appropriate measured depolarization interval in accordance with whether the synchronized protection period is initiated by a sense or a pace; and

, classify measured depolarization intervals as to type depending upon a measured heart rate, with the synchronized chamber protection period being set during each cardiac cycle to approximately equal a measured depolarization interval whose type corresponds with a presently measured heart rate.

8. The device of claim 7 wherein the controller programmed to:

periodically measure depolarization intervals and classify each as to type;

average multiple measured depolarization intervals of the same type; and

,

use an initially programmed value for setting the synchronized chamber protection period if a depolarization interval of appropriate type has not yet been measured.

9. The device of claim 1 wherein the synchronized chamber protection period expires during each cardiac cycle upon detection of a repolarization in the synchronized chamber.

10. The device of claim 9 wherein a maximum duration of the synchronized chamber protection period is specified such that the period expires eventually expires even if no repolarization in the synchronized chamber is detected.

11. A method for operating a cardiac rhythm management device, comprising:

sensing intrinsic depolarizations in heart chambers designated as a rate chamber and a synchronized chamber and generating sense signals in accordance therewith;

pacing the synchronized chamber in accordance with a synchronized pacing mode based upon rate chamber events, wherein pacing of the synchronized chamber is inhibited during a synchronized chamber protection period that is initiated by a synchronized chamber sense or pace; and

,

adjusting the duration of the synchronized chamber protection period based upon detection of a repolarization in the synchronized chamber.

12. The method of claim 11 further comprising adjusting the synchronized chamber protection period by setting it to approximately equal a measured depolarization interval in the synchronized chamber, the depolarization interval starting with a depolarization in the synchronized chamber and ending with a detected repolarization.

13. The method of claim 12 further comprising classifying measured depolarization intervals as to type depending upon whether the depolarization is due to a sense or pace in the synchronized chamber, with the synchronized chamber protection period being set during each cardiac cycle to approximately equal an appropriate measured depolarization interval in accordance with whether the synchronized protection period is initiated by a sense or a pace.

14. The method of claim 12 further comprising classifying measured depolarization intervals as to type depending upon a measured heart rate, with the synchronized chamber protection period being set during each cardiac cycle to approximately equal a measured depolarization interval whose type corresponds with a presently measured heart rate.

15. The method of claim 12 further comprising periodically measuring depolarization intervals used for setting the synchronized chamber protection period.

16. The method of claim 12 further comprising averaging a plurality of measured depolarization intervals.

17. The method of claim 12 further comprising:

classifying measured depolarization intervals as to type depending upon whether the depolarization is due to a sense or pace in the synchronized chamber, with the synchronized chamber protection period being set during each cardiac cycle to approximately equal an appropriate measured depolarization interval in accordance with whether the synchronized protection period is initiated by a sense or a pace; and

,

classifying measured depolarization intervals as to type depending upon a measured heart rate, with the synchronized chamber protection period being set during each cardiac cycle to approximately equal a measured depolarization interval whose type corresponds with a presently measured heart rate.

18. The method of claim 17 further comprising:

periodically measuring depolarization intervals and classify each as to type;

averaging multiple measured depolarization intervals of the same type; and

,

using an initially programmed value for setting the synchronized chamber protection period if a depolarization interval of appropriate type has not yet been measured.

19. The method of claim 11 wherein the synchronized chamber protection period expires during each cardiac cycle upon detection of a repolarization in the synchronized chamber.

20. The method of claim 19 wherein a maximum duration of the synchronized chamber protection period is specified such that the period expires eventually expires even if no repolarization in the synchronized chamber is detected.

21. The method of claim 11 wherein right and left ventricles are the rate and synchronized chambers, respectively, and the synchronized chamber protection period is a left ventricular protection period.

22. The method of claim 11 wherein the paired atria are the rate and synchronized chambers.

23. The method of claim 11 further comprising pacing one or more additional synchronized pacing sites in accordance with a synchronized pacing mode based upon rate chamber events and wherein pacing of each synchronized site is inhibited during a synchronized chamber protection period that is initiated by a sense or pace at the synchronized site and that is adjusted based upon detection of a repolarization at the synchronized site.

24. The method of claim 11 wherein the synchronized pacing mode is an offset synchronized pacing mode.

25. The method of claim 11 wherein the synchronized pacing mode is a synchronized chamber-only synchronized pacing mode.

26. The method of claim 11 wherein the synchronized pacing mode is a triggered synchronized pacing mode.

27. The method of claim 11 wherein a pace to the synchronized chamber may be triggered by a synchronized chamber sense and wherein the synchronized chamber protection period starts only after a specified delay from such a triggering event, which allows triggered pacing but prevents pacing during the vulnerable period of the synchronized chamber.