Apparatus and methods for treating stroke and controlling cerebral flow characteristics
First Claim
1. Apparatus suitable for manipulating cerebral blood flow characteristics, the apparatus comprising:
- a catheter having proximal and distal ends, a lumen extending therebetween, and an occlusive element affixed to the distal end, the occlusive element having an opening that communicates with the lumen, the occlusive element having a contracted position suitable for transluminal insertion and an expanded position wherein the occlusive element occludes antegrade flow in a vessel; and
at least one flow control device having proximal and distal ends and a flow control element disposed at the distal end, the flow control device, when deployed, controlling flow in the mid-cerebral artery.
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Accused Products
Abstract
Apparatus and methods for treatment of stroke are provided. In a preferred embodiment, the present invention disposes at least one catheter having a distal occlusive member in either the common carotid artery (CCA) or both the vertebral artery (VA) and the CCA on the hemisphere of the cerebral occlusion. Blood flow in the opposing carotid and/or vertebral arteries may be inhibited. Retrograde or antegrade flow may be provided through either catheter independently to effectively control cerebral flow characteristics. Under such controlled flow conditions, a thrombectomy device may be used to treat the occlusion, and any emboli generated are directed into the catheter(s).
114 Citations
25 Claims
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1. Apparatus suitable for manipulating cerebral blood flow characteristics, the apparatus comprising:
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a catheter having proximal and distal ends, a lumen extending therebetween, and an occlusive element affixed to the distal end, the occlusive element having an opening that communicates with the lumen, the occlusive element having a contracted position suitable for transluminal insertion and an expanded position wherein the occlusive element occludes antegrade flow in a vessel; and
at least one flow control device having proximal and distal ends and a flow control element disposed at the distal end, the flow control device, when deployed, controlling flow in the mid-cerebral artery. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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18. A method for manipulating cerebral blood flow characteristics, the method comprising:
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providing apparatus comprising a catheter having proximal and distal ends, a lumen extending therebetween, and an occlusive element affixed to the distal end, and further providing at least one flow control device having proximal and distal ends, and a flow control element disposed at the distal end;
positioning the distal end of the flow control device in a selected vessel in a contracted state;
positioning the distal end of the catheter in a selected vessel in a contracted state;
deploying the occlusive element affixed to the catheter to occlude antegrade flow in the selected vessel; and
deploying the flow control element to control perfusion in the mid-cerebral artery. - View Dependent Claims (19, 20, 21, 22, 23, 24, 25)
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Specification