Flat implant for use in surgery

• US 20030040809A1
• Filed: 07/21/2002
• Published: 02/27/2003
• Est. Priority Date: 03/20/1999
• Status: Abandoned Application

• Current Assignee: Aesculap AG (B. Braun Holding GmbH & Co. KG)
• Original Assignee: Aesculap AG (B. Braun Holding GmbH & Co. KG)
• Inventors: Bertholdt, Guenther, Goldmann, Helmut, Langanke, Dennis, Weis, Christine
• Application Number:
  US10/201,440
• Publication Number:
  US 20030040809A1
• Time in Patent Office: Days
• US Class Current: 623/23.76
• CPC Class Codes: A61F 2/0063 Implantable repair or support meshes, e.g. hernia meshes
• CPC Class Codes: A61F 2/0077 Special surfaces of prostheses, e.g. for improving ingrowth A61F2/30767 takes precedence
• CPC Class Codes: A61F 2250/0051 differing in tissue ingrowth capacity, e.g. made from both ingrowth-promoting and ingrowth-preventing parts
• CPC Class Codes: D04B 21/04 characterised by thread material
• CPC Class Codes: D10B 2403/0112 One smooth surface, e.g. laminated or coated
• CPC Class Codes: D10B 2509/08 Hernia repair mesh

Abstract

A flat implant for use in surgery is described. The implant includes a flexible fabric comprising two sides and having on one side a substantially closed surface and on the other side a three-dimensional microstructure permitting a growing in of cells. The implant can be more particularly used for the treatment of wall defects in body cavities, such as abdominal wall defects.

Claims

1. A flat implant for use in surgery, the implant comprising a flexible fabric comprising two sides and having on one side a substantially closed surface and on the other side a three-dimensional microstructure permitting a growing in of cells, wherein the substantially closed surface comprises micropores, the micropores being so small that they permit an exchange of materials, but substantially prevent the growing in of cells, and wherein an additional adhesion prevention is provided by a bioabsorbable component which has a sealing effect.

4. The implant according to claim 1, wherein the three-dimensional microstructure has back-engageable points for the growing in of cells.

5. The implant according to claim 1, wherein the flexible fabric is formed by a porous, flexible structural material, and the three-dimensional microstructure is formed by the exposed surface structure of the structural material.

6. The implant according to claim 5, wherein the flexible structural material is made of polypropylene.

7. The implant according to claim 5, wherein the flexible structural material has elasticity characteristics.

8. The implant according to claim 5, wherein the flexible structural material is a textile fabric.

9. The implant according to claim 8, wherein the flexible structural material is a porous textile support.

10. The implant according to claim 9, wherein the porous textile support is made of polypropylene monofilaments.

11. The implant according to claim 5, wherein the flexible structural material has on at least the side with the three-dimensional microstructure an open textile structure capable of use with vascular implants and which is formed by one or more of textured yarns, float stitches and velour loops.

12. The implant according to claim 8, wherein the textile fabric has open pores sized up to 3 mm in diameter.

13. The implant according to claim 12, wherein the pores are sized 0.5 to 2 mm.

14. The implant according to claim 1, wherein the micropores have a pore size in the range from 10 μ

m to 30 μ

m.

15. The implant according to claim 1, wherein the flexible fabric is a woven fabric which at least on the three-dimensionally microstructured side has exposed fibers or threads serving as an anchoring for cells.

16. The implant according to claim 1, wherein the flexible fabric is a knitted fabric which at least on the three-dimensionally microstructured side has exposed fibers or threads serving as an anchoring for cells.

17. The implant according to claim 14, wherein the knitted fabric is a warp-knitted fabric.

18. The implant according to claim 1, wherein the flexible fabric is a velour.

19. The implant according to claim 18, wherein the velour is a double velour.

20. The implant according to claim 19, wherein the double velour has on the structured side preferably a larger pile height than on the substantially closed side of the implant.

21. The implant according to claim 8, wherein the textile fabric has a thickness from 0.4 to 1.0 mm.

24. The implant according to claim 1, wherein the substantially closed surface layer is made of polyurethane.

25. The implant according to claim 24, wherein the surface layer is a polyurethane spray coating applied to one side of the flat implant.

26. The implant according to claim 24, wherein the polyurethane surface layer has a thickness of 0.1 mm to 0.4 mm.

28. The implant according to claim 1, wherein the additional adhesion prevention is provided on the outer surface of the substantially closed surface.

29. The implant according to claim 1, wherein the bioabsorbable component is at least one component selected from the group of polyvinyl alcohol, polymers and copolymers of organic hydroxyesters.

30. The implant according to claim 1, wherein the bioabsorbable component is a spray coating.

31. The implant according to claim 29, wherein the additional adhesion prevention is a PVA coating on top of a polyurethane spray coating.

32. The implant according to claim 1, wherein the bioabsorbable component is effective in adhesion prevention for a period of 10 to 30 days after surgery.

33. The implant according to claim 1, wherein the implant in the absence of the bioabsorbable material has an air permeability of 5 to 100 ml of air/cm².min for a pressure difference of 1.2 kPascal.

34. The implant according to claim 1, wherein the implant has fraying proof edges formed by one or more of processing, bonding and welding in a fraying-proof manner.

35. The implant according to claim 1, wherein the implant has a total thickness of approximately 0.1 to 1.2 mm, the thickness of the substantially closed surface preferably being 3 to 15% thereof.

36. The implant according to claim 1, wherein the flexible fabric has at least one of a woven and knitted basic weave with a thickness of 0.05 to 0.4 mm and an at least unilaterally open structure with a thickness of 0.05 to 0.8 mm.

37. The implant according to claim 1, wherein the substantially closed surface is of completely resorbable material.

38. The implant according to claim 1, wherein the implant is capable of use in the treatment of wall defects in body cavities.

39. The implant according to claim 38, wherein the implant is capable of use in the treatment of abdominal wall defects.

2. The implant according to clam 1, wherein the substantially closed surface is formed by at least one surface layer connected to the flexible fabric.

3. The implant according to claim 2, wherein the fabric comprises at least one coating and the at least one surface layer is provided by at least one coating of the fabric.

22. The implant according to claim 2, wherein the surface layer is a spray coating.

23. The implant according to claim 22, wherein the spray coating is a sprayed web of a polymer, said polymer being one of soluble and dispersible in a medium, wherein the medium is at least one of non-aqueous, liquid and volatile.

27. The implant according to claim 2, wherein the substantially closed surface is formed by multiple surface layers and the multiple surface layers have similar elasticity characteristics.

40. A hernial implant comprising a flexible flat three-layered structure including a three-dimensional textile support microstructure permitting a growing in of cells, a substantially closed layer or micropores having a pore size to permit an exchange of materials, but substantially prevent the growing in of cells, and superimposed thereon an additional top layer of a bioabsorbable component which has a sealing effect for adhesion prevention.