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Method of diagnosing of exposure to toxic agents by measuring distinct pattern in the levels of expression of specific genes

  • US 20030044790A1
  • Filed: 06/07/2001
  • Published: 03/06/2003
  • Est. Priority Date: 02/05/1999
  • Status: Abandoned Application
First Claim
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1. A method of pre-symptom diagnosis of exposure to a toxic agent comprising:

  • obtaining a sample of mammalian body fluid or tissue from a subject;

    detecting a pattern of gene expression or protein expression present in said sample;

    comparing the pattern of gene or protein expression from said sample with a library of known patterns of gene or protein expressions for toxic agents; and

    determining whether the subject has been exposed to a toxic agent and if said subject has been exposed to a toxic agent, identifying said toxic agent based on information in said library.

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