System and method for adaptive drug delivery
First Claim
1. A system for controlling the administration of medication to a patient to achieve and maintain a target effect in said patient, the system comprising:
- a sensor package having one or more sensors, said sensors being configured to sense an attribute of said patient and to provide a parameter indicating the attribute being sensed;
a medication delivery unit configured to administer said medication to said patient to achieve a concentration of said medication in said patient; and
a medication delivery controller having an input coupled to said sensor package and an output coupled to said medication delivery unit, said medication delivery controller being configured to accept said one or more parameters from said sensor package, to determine a target concentration level of said medication to achieve said target effect, and to control said medication delivery unit to deliver said medication at a rate determined to achieve said target concentration level of said medication in said patient.
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Accused Products
Abstract
A system and method for controlling the administration of medication to a patient utilizes adaptive feedback to achieve and maintain a target effect in said patient. A sensor package having one or more sensors is used to sense an attribute of the patient and to provide a parameter indicating the attribute being sensed. A medication delivery controller accepts one or more parameters from the sensor package and uses these parameters to determine the effect of a medication on a patient and the concentration level of medication that will achieve a desired effect. The medication delivery controller controls the medication delivery unit to deliver the medication at a rate determined to achieve said target concentration level of said medication in said patient. If the patient'"'"'s response to a given medication changes as a result of external stimuli, the medication delivery controller can detect this change and determine a new concentration level of medication which will achieve the desired effect. The medication delivery controller can steer the medication delivery unit to administer an amount of medication to reach this new concentration level.
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Citations
50 Claims
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1. A system for controlling the administration of medication to a patient to achieve and maintain a target effect in said patient, the system comprising:
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a sensor package having one or more sensors, said sensors being configured to sense an attribute of said patient and to provide a parameter indicating the attribute being sensed;
a medication delivery unit configured to administer said medication to said patient to achieve a concentration of said medication in said patient; and
a medication delivery controller having an input coupled to said sensor package and an output coupled to said medication delivery unit, said medication delivery controller being configured to accept said one or more parameters from said sensor package, to determine a target concentration level of said medication to achieve said target effect, and to control said medication delivery unit to deliver said medication at a rate determined to achieve said target concentration level of said medication in said patient. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A method for controlling the administration of medication to a patient to achieve and maintain a desired effect in said patient, the method comprising the steps of:
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computing a first patient response profile, said patient response profile indicating the patient'"'"'s individualized response to said medication;
using the first patient response profile to determine a first concentration level of said medication to maintain said target effect in said patient;
determining whether the patient'"'"'s response to said first concentration level of said medication has changed;
computing a second patient response profile reflecting the patient'"'"'s new individualized response to said medication; and
using said second patient response profile to determine a new concentration level of medication to maintain said target effect in said patient. - View Dependent Claims (10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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22. A medication delivery controller for controlling the administration of medication to a patient to achieve and maintain a target effect in said patient, the controller comprising:
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a sensor interface configured to receive one or more patient parameters from a sensor package, a processor coupled to said data interface configured to determine a target concentration level of said medication to achieve said target effect and to determine a medication delivery rate to achieve said target concentration level of said medication in said patient; and
a data output port coupled to said processor to forward instructions to a medication delivery unit to deliver said medication at said medication delivery rate determined by said processor. - View Dependent Claims (23, 24, 25, 26, 27, 28, 29, 30, 31)
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32. A medication delivery controller for controlling the administration of medication to a patient to achieve and maintain a target effect in said patient, the controller comprising:
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means for detecting one or more patient parameters;
means for determining a target concentration level of said medication to achieve said target effect based on said one or more patient parameters;
means for determining a medication delivery rate to achieve said target concentration level of said medication in said patient. - View Dependent Claims (33, 34, 35, 37, 38, 39, 40)
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36. The medication delivery controller of claim 36, wherein said means for calculating a patient response profile comprises means for instructing said medication delivery unit to provide at least one level of concentration of medication to said patient and to measure the effect of said at least one level of concentration based on one or more parameters received from said one or more sensors.
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41. A processor-based system for running program code to control the administration of medication to a patient to achieve and maintain a target effect in said patient, the program code comprising:
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program code for determining whether the patient'"'"'s response to a target concentration level of said medication has changed;
program code for computing a patient response profile reflecting the patient'"'"'s new individualized response to said medication; and
program code for using said second patient response profile to determine a new concentration level of medication to maintain said target effect in said patient. - View Dependent Claims (42, 43, 44, 45)
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46. A medication delivery controller configured to perform a method for controlling the administration of medication to a patient to achieve and maintain a target effect in said patient, the method comprising:
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receiving one or more patient parameters from a sensor package, the parameters indicating one or more attributes sensed from the patient;
determining a target concentration level of said medication to achieve said target effect based on said one or more received parameters;
determining a medication delivery rate to achieve said target concentration level of said medication in said patient; and
instructing a medication delivery unit to deliver said medication at said medication delivery rate determined by said processor. - View Dependent Claims (47, 48, 49, 50)
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Specification