Micro perfusion device
First Claim
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1. A micro perfusion device for obtaining at least one constituent of a body fluid using a subcutaneously positioned perfusion catheter, the device comprising:
- a) a casing;
b) a perfusate supply;
c) a hollow injection needle configured to protrude through the casing and having a front needle opening and a rear needle opening, the injection needle configured to be slideable from a front sliding position in which the needle protrudes beyond a distal end of the perfusion catheter to a rear sliding position in which the front needle opening is disposed within the perfusion catheter, wherein the rear needle opening forms a fluid connection from the perfusate supply to the injection needle at least in the rear sliding position of the injection needle;
d) the perfusion catheter which projects from the casing and surrounds the injection needle; and
e) a discharge channel formed in the casing, the discharge channel being fluidly connected to the perfusion catheter for discharging a perfusate.
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Abstract
A micro perfusion device and method for obtaining at least one constituent of a body fluid. The at least one constituent is obtained using a subcutaneously-positioned perfusion catheter into which perfusate is introduced by a supply channel and an injection needle. The perfusate absorbs the at least one constituent as it flows out of the perfusion catheter and through a discharge channel.
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Citations
29 Claims
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1. A micro perfusion device for obtaining at least one constituent of a body fluid using a subcutaneously positioned perfusion catheter, the device comprising:
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a) a casing;
b) a perfusate supply;
c) a hollow injection needle configured to protrude through the casing and having a front needle opening and a rear needle opening, the injection needle configured to be slideable from a front sliding position in which the needle protrudes beyond a distal end of the perfusion catheter to a rear sliding position in which the front needle opening is disposed within the perfusion catheter, wherein the rear needle opening forms a fluid connection from the perfusate supply to the injection needle at least in the rear sliding position of the injection needle;
d) the perfusion catheter which projects from the casing and surrounds the injection needle; and
e) a discharge channel formed in the casing, the discharge channel being fluidly connected to the perfusion catheter for discharging a perfusate. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. A micro perfusion device for obtaining at least one constituent of a body fluid using a subcutaneously positioned perfusion catheter, the device comprising:
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a) a casing;
b) the perfusion catheter projecting from the casing;
c) a hollow injection needle slideably disposed within the perfusion catheter in a position ranging from a front sliding position to a rear sliding position, the injection needle in the front sliding position being configured to protrude from a distal end of the perfusion catheter such that a distal end of the injection needle is external to the perfusion catheter;
d) a supply channel fluidly connected to the injection needle in the rear sliding position through a rear needle opening in the injection needle, the rear sliding position being configured to allow a perfusate to flow from the supply channel through the injection needle and into the perfusion catheter; and
e) a discharge channel formed in the casing, the discharge channel being connected to the perfusion catheter for discharging the perfusate. - View Dependent Claims (15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26)
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27. A method of obtaining at least one constituent of a body fluid, comprising:
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(a) providing a hollow injection needle slideably disposed in a casing, the casing being configured to be placed against skin of a patient;
(b) providing a perfusion catheter configured to encompass the injection needle;
(c) inserting the perfusion catheter into a tissue containing the at least one constituent when a distal end of the injection needle is protruding from a distal end of the perfusion catheter;
(d) retracting the injection needle until a fluid connection is established between a supply channel and the injection needle;
(e) causing perfusate to flow through the supply channel and the injection needle and out of a distal opening in the injection needle into a lumen between the injection needle and the perfusion catheter;
(f) absorbing the at least one constituent from the body fluid into the perfusate through openings in the perfusion catheter, wherein the at least one constituent is pulled into the lumen across a concentration gradient created as the perfusate is guided away from the distal opening in the injection needle; and
(g) causing the perfusate and the at least one constituent to flow out of the lumen through a discharge channel. - View Dependent Claims (28, 29)
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Specification