Substrate for fluorescence analysis
First Claim
1. A substrate for fluorescence analysis, comprising a surface layer of silicon dioxide attached to a support layer.
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Accused Products
Abstract
The present invention relates to an improved substrate for use in detection of fluorescence. More specifically the improved substrate exhibits a supported surface layer of silicon dioxide on a silicon support material, on another solid support material, or on a silicon layer supported on another solid support material. The inventive substrate allows for a significantly higher sensitivity to be obtained when used in fluorescence analysis. The invention also relates to a method of preparing the inventive substrate, which substrate in one embodiment of the invention takes the form of silicon a slide exhibiting an oxidized surface. The invention also relates to the application of the inventive substrate in microarray analysis.
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Citations
14 Claims
- 1. A substrate for fluorescence analysis, comprising a surface layer of silicon dioxide attached to a support layer.
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11. A method for preparing a substrate for fluorescence analysis exhibiting a surface layer of silicon dioxide attached to a support layer comprising the steps of:
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a) providing a silicon layer; and
b) oxidizing a surface of the silicon layer in an oxygen containing atmosphere under a high temperature ranging from 600 to 1300°
C. - View Dependent Claims (12, 13, 14)
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Specification