Device for holding a substrate

• US 20030059348A1
• Filed: 03/11/2002
• Published: 03/27/2003
• Est. Priority Date: 03/13/2001
• Status: Active Grant

• Current Assignee: PamGene B.V. (VitrOmics Healthcare Holding BV)
• Original Assignee: PamGene B.V. (VitrOmics Healthcare Holding BV)
• Inventors: Carpay, Wilhelmus Marinus, van Damme, Hendrik Sibolt
• Granted Patent: US 7,105,134 B2
• Time in Patent Office: Days
• US Class Current: 422/102
• CPC Class Codes: B01L 2200/027 for microfluidic devices
• CPC Class Codes: B01L 2300/0681 Filter
• CPC Class Codes: B01L 2300/0822 Slides
• CPC Class Codes: B01L 2400/0406 capillary forces
• CPC Class Codes: B01L 3/5023 with a sample being transported to, and subsequently stored in an absorbent for analysis
• CPC Class Codes: B01L 3/50255 Multi-well filtration
• CPC Class Codes: B01L 9/527 for microfluidic devices, e.g. used for lab-on-a-chip

Abstract

A device for holding a substrate comprises upper and lower plates adapted to receive the substrate sandwiched in the interface between the plates. Each plate has at least one opening with a projecting rim surrounding the opening and directed away from the interface. The openings in the upper and lower plates are preferably at least partially aligned in the sandwiched position of the plates. Each opening in the lower plate can be provided with a shielding member partially shielding the opening of the lower plate.

Claims

1. A device for holding a substrate, characterized by upper and lower plates adapted to receive the substrate sandwiched in the interface between the plates, each plate having at least one opening with a projecting rim surrounding the opening and directed away from the interface, wherein the openings in the upper and lower plates are at least partially aligned in the sandwiched position of the plates.

2. The device according to claim 1, wherein the openings are circular and the projecting rims are cylindrical structures.

3. The device according to claim 1, wherein each opening in the lower plate is provided with a shielding member partially shielding the opening of the lower plate.

4. The device according to claim 2, wherein each opening in the lower plate is provided with a shielding member partially shielding the opening of the lower plate.

5. The device according to claim 3, wherein each shielding member has an upper surface inclined at an angle of inclination with respect to the interface of the plates.

6. The device according to claim 4, wherein each shielding member has an upper surface inclined at an angle of inclination with respect to the interface of the plates.

7. The device according to claim 5, wherein the angle of inclination of the upper surface of the shielding member is at least 5°

.

8. The device according to claim 6, wherein the angle of inclination of the upper surface of the shielding member is at least 5°

.

9. The device according to claim 3, wherein the opening(s) in the lower plate is (are) staggered with respect to the openings in the upper plate, wherein the shielding member(s) in the lower plate openings fully shield the lower plate opening(s) with respect to the upper plate openings.

10. The device according to claim 5, wherein the opening(s) in the lower plate is (are) staggered with respect to the openings in the upper plate, wherein the shielding member(s) in the lower plate openings fully shield the lower plate opening(s) with respect to the upper plate openings.

11. The device according to claim 7, wherein the opening(s) in the lower plate is (are) staggered with respect to the openings in the upper plate, wherein the shielding member(s) in the lower plate openings fully shield the lower plate opening(s) with respect to the upper plate openings.

12. The device according to claim 3, wherein the shielding member(s) have a wedge-shaped cross-section.

13. The device according to claim 5, wherein the shielding member(s) have a wedge-shaped cross-section.

14. The device according to claim 7, wherein the shielding member(s) have a wedge-shaped cross-section.

15. The device according to claim 9, wherein the shielding member(s) have a wedge-shaped cross-section.