Hybridization apparatus and method for detecting nucleic acid in sample using the same
First Claim
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1. An automatic nucleic acid hybridization apparatus comprising:
- (A) a denature station having a reaction vessel holder and a heating-cooling device;
(B) an annealing station having a reaction vessel holder and a heating-cooling device;
(C) a magnetic separation station having a reaction vessel holder and a magnetic force controller;
(D) a tip rack storing station having a tip rack;
(E) a washing solution station having a washing solution reservoir;
(F) a waste solution station having a waste solution reservoir; and
(G) a head station having an arm unit movable in X-Z directions, the arm unit including a tip setting mechanism having a plurality of tip nozzles for respective tips to be attached to or detached from the nozzles, a mechanism for the attached tips to suck and/or inject treatment solution, and a robot-hand mechanism capable of holding and releasing a reaction vessel.
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Abstract
A hybridization apparatus includes at least (A) a reaction station having a reaction vessel holder, a heating-cooling device, and a magnetic force controller, (B) a tip rack/waste solution station having a tip rack and a waste solution reservoir, (C) a washing solution station having a washing solution reservoir and a heating-cooling device, and (D) a head station having an arm unit movable in X-Z directions, the arm unit including a tip setting mechanism having a 1o plurality of tip nozzles for respective tips to be attached to or detached from, and a mechanism for the attached tips to suck and inject treatment solution.
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Citations
19 Claims
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1. An automatic nucleic acid hybridization apparatus comprising:
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(A) a denature station having a reaction vessel holder and a heating-cooling device;
(B) an annealing station having a reaction vessel holder and a heating-cooling device;
(C) a magnetic separation station having a reaction vessel holder and a magnetic force controller;
(D) a tip rack storing station having a tip rack;
(E) a washing solution station having a washing solution reservoir;
(F) a waste solution station having a waste solution reservoir; and
(G) a head station having an arm unit movable in X-Z directions, the arm unit including a tip setting mechanism having a plurality of tip nozzles for respective tips to be attached to or detached from the nozzles, a mechanism for the attached tips to suck and/or inject treatment solution, and a robot-hand mechanism capable of holding and releasing a reaction vessel. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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10. An automatic nucleic acid hybridization apparatus, comprising:
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(A′
) a reaction station having a reaction vessel holder, a heating-cooling device, and a magnetic force controller;
(B′
) a tip rack/waste solution station having a tip rack and a waste solution reservoir;
(C′
) a washing solution station having a washing solution reservoir and a heating-cooling device; and
(D′
) a head station having an arm unit movable in X-Z directions, the arm unit comprising a tip setting mechanism having a plurality of tip nozzles for respective tips to be attached to or detached from, and a mechanism for the attached tips to suck and/or inject treatment solution. - View Dependent Claims (11, 12, 13, 14, 15, 16, 17, 18, 19)
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Specification