Method and apparatus for patient temperature control employing administration of anti-shivering agents
First Claim
1. A method of changing the temperature of a human body, comprising:
- inserting a catheter having a heat transfer element into a vein of a patient;
circulating a working fluid through the catheter and the heat transfer element, the working fluid having a temperature different from the patient temperature;
administering a therapeutic amount of meperidine, whereby shivering is lessened.
10 Assignments
0 Petitions
Accused Products
Abstract
Embodiments of the invention provide a system for temperature control of the human body. The system includes an indwelling catheter with a tip-mounted heat transfer element. The catheter is fluidically coupled to a console that provides a heated or cooled heat transfer working fluid to exchange heat with the heat transfer element, thereby heating or cooling blood. The heated or cooled blood then heats or cools the patient'"'"'s body or a selected portion thereof. In particular, strategies for providing cooling while reducing shivering are disclosed, including administration of various drugs and drug combinations.
-
Citations
28 Claims
-
1. A method of changing the temperature of a human body, comprising:
-
inserting a catheter having a heat transfer element into a vein of a patient;
circulating a working fluid through the catheter and the heat transfer element, the working fluid having a temperature different from the patient temperature;
administering a therapeutic amount of meperidine, whereby shivering is lessened. - View Dependent Claims (2, 3, 25)
-
-
4. A method of changing the temperature of a human body, comprising:
-
inserting a catheter having a heat transfer element into a vein of a patient;
circulating a working fluid through the catheter and the heat transfer element, the working fluid having a temperature different from the patient temperature;
administering a therapeutic amount of a prodine, whereby shivering is lessened. - View Dependent Claims (5, 6)
-
-
7. A method of changing the temperature of a human body, comprising:
-
inserting a catheter having a heat transfer element into a vein of a patient;
circulating a working fluid through the catheter and the heat transfer element, the working fluid having a temperature different from the patient temperature;
administering a therapeutic amount of fentanyl, whereby shivering is lessened. - View Dependent Claims (8, 9)
-
-
10. A method of changing the temperature of a human body, comprising:
-
inserting a catheter having a heat transfer element into a vein of a patient;
circulating a working fluid through the catheter and the heat transfer element, the working fluid having a temperature different from the patient temperature;
administering a therapeutic amount of an opioid, whereby shivering is lessened. - View Dependent Claims (11, 12)
-
-
13. A method of changing the temperature of a human body, comprising:
-
inserting a catheter having a heat transfer element into a vein of a patient;
circulating a working fluid through the catheter and the heat transfer element, the working fluid having a temperature different from the patient temperature;
administering a therapeutic amount of a drug selected from the group consisting essentially of prodine, fentanyl, and an opioid, in combination with a delta opiate receptor antagonist, whereby shivering is lessened. - View Dependent Claims (14, 15, 16)
-
-
17. A method of changing the temperature of a human body, comprising:
-
inserting a catheter having a heat transfer element into a vein of a patient;
circulating a working fluid through the catheter and the heat transfer element, the working fluid having a temperature different from the patient temperature;
administering a therapeutic amount of a (+) isomer of a prodine in which a hydroxyl has been added to the phenyl ring, whereby shivering is lessened. - View Dependent Claims (18, 19)
-
-
20. A method of changing the temperature of a human body, comprising:
-
inserting a catheter having a heat transfer element into a vein of a patient;
circulating a working fluid through the catheter and the heat transfer element, the working fluid having a temperature different from the patient temperature;
administering a therapeutic amount of a (+) beta isomer of a prodine in which the 3-methyl group is replaced with an n-propyl or allyl group, whereby shivering is lessened.
-
-
21. A method of changing the temperature of a human body, comprising:
-
inserting a catheter having a heat transfer element into a vein of a patient;
circulating a working fluid through the catheter and the heat transfer element, the working fluid having a temperature different from the patient temperature;
administering a therapeutic amount of a isomer of a cis-picenadol. - View Dependent Claims (22, 23)
-
-
24. A method of changing the temperature of a human body, comprising:
-
inserting a catheter having a heat transfer element into a vein of a patient;
circulating a working fluid through the catheter and the heat transfer element, the working fluid having a temperature different from the patient temperature;
administering a therapeutic amount of a isomer of tramadol.
-
-
26. A method of changing the temperature of a human body, comprising:
-
inserting a catheter having a heat transfer element into a vein of a patient;
circulating a working fluid through the catheter and the heat transfer element, the working fluid having a temperature different from the patient temperature;
administering a therapeutic amount of a isomer of nefopam. - View Dependent Claims (27, 28)
-
Specification